Swept-Source Anterior Segment Optical Coherence Tomography of a Vascularized Syphilitic Iris Lesion.

IF 2.6 4区医学 Q2 OPHTHALMOLOGY

Ocular Immunology and Inflammation Pub Date : 2025-06-11 DOI:10.1080/09273948.2025.2514693

Saitiel Sandoval Gonzalez, Weilin Song, Joseph K Privratsky, Jack Lemon, Edmund Tsui

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Abstract

Purpose: To describe the appearance and resolution of a vascularized iris nodule in a case of ocular syphilis with swept-source anterior segment optical coherence tomography (SS AS-OCT) imaging.

Methods: Case report.

Results: A 73-year-old male with a history of ocular syphilis presented with anterior uveitis of the left eye characterized by mutton fat keratic precipitates, anterior chamber cells, hypopyon mixed with hemorrhage, and a vascularized iris nodule. SS AS-OCT similarly showed keratic precipitates, anterior chamber cells, and an iris lesion with anterior hyperreflectivity and shadowing. Systemic workup revealed a new syphilis infection with rapid plasma reagin (RPR) titer of 1:512. After completing a 14-day course of intravenous penicillin and topical steroid treatment, there was resolution of these ocular findings.

Conclusion: Ocular syphilis should be considered on the differential diagnosis for vascularized iris lesions. Our case demonstrates SS-AS-OCT findings in this rare presentation of ocular syphilis.

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血管化梅毒性虹膜病变的扫描源前段光学相干断层扫描。

目的：用扫源前段光学相干断层扫描（SS AS-OCT）描述眼梅毒一例血管化虹膜结节的外观和分辨率。方法：病例报告。结果：73岁男性，有眼梅毒病史，左眼前葡萄膜炎，表现为羊肉脂肪角化沉淀、前房细胞、垂体后叶混合性出血和血管化虹膜结节。SS AS-OCT同样显示角状沉淀、前房细胞和虹膜病变，伴有前反射率高和阴影。全身检查发现1例梅毒新发感染，快速血浆反应（RPR）滴度为1:12 12。在完成14天的静脉注射青霉素和局部类固醇治疗后，这些眼部发现得到了解决。结论：虹膜血管化病变的鉴别诊断应考虑眼梅毒。我们的病例证实了SS-AS-OCT在这个罕见的眼部梅毒的表现。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Ocular Immunology and Inflammation 医学-眼科学

CiteScore

6.20

自引率

15.20%

发文量

285

审稿时长

6-12 weeks

期刊介绍： Ocular Immunology & Inflammation ranks 18 out of 59 in the Ophthalmology Category.Ocular Immunology and Inflammation is a peer-reviewed, scientific publication that welcomes the submission of original, previously unpublished manuscripts directed to ophthalmologists and vision scientists. Published bimonthly, the journal provides an international medium for basic and clinical research reports on the ocular inflammatory response and its control by the immune system. The journal publishes original research papers, case reports, reviews, letters to the editor, meeting abstracts, and invited editorials.