Protocolo terapéutico de las vasculitis con afectación visceral

Abstract

Vasculitides with visceral involvement are severe and complex forms of vasculitis that entail target organ involvement. They are associated with a worse prognosis. Treatment should be early and individualized to attempt to achieve rapid remission and prevent irreversible organ damage. The mainstay of treatment is high-dose corticosteroids and various immunosuppressants. This protocol describes the treatment of severe forms with organ involvement of the major primary vasculitides, including giant cell arteritis, Takayasu's arteritis, anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides, central nervous system vasculitides, anti-glomerular basement membrane (GBM) disease, and IgA vasculitides. Its objective is to provide guidelines for the management of these diseases that will help clinicians in their routine clinical practice.