Prevalence and prognostic impact of cardiac resonance abnormalities in myotonic dystrophy patients

IF 2.7 4区医学 Q2 CLINICAL NEUROLOGY

Neuromuscular Disorders Pub Date : 2025-05-31 DOI:10.1016/j.nmd.2025.105396

Vincenzo Russo , Alfredo Mauriello , Roberta Bottino , Antonio Giordano , Michal Marchel , Antonello D’Andrea , Théo Pezel , Gerardo Nigro , Santo Dellegrottaglie

引用次数: 0

Abstract

Myotonic dystrophy (DM) is an autosomal dominant inherited neuromuscular disorder characterized by progressive muscular weakness and multisystem involvement. Cardiac involvement is recorded in about 80 % of cases and often precedes the involvement of skeletal muscle. Cardiovascular magnetic resonance (CMR) has been recently included as a recommended test in the cardiac assessment of DM patients at the time of diagnosis, and subsequently with periodic testing. Our systematic review aims to describe the prevalence and prognosis of disease-related CMR abnormalities in DM patients.

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强直性肌营养不良患者心脏共振异常的患病率及对预后的影响

肌强直性营养不良（DM）是一种常染色体显性遗传性神经肌肉疾病，以进行性肌肉无力和多系统受累为特征。约80%的病例累及心脏，通常先于骨骼肌。心血管磁共振（CMR）最近被推荐用于糖尿病患者诊断时的心脏评估，并随后进行定期检查。我们的系统综述旨在描述糖尿病患者疾病相关CMR异常的患病率和预后。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Neuromuscular Disorders 医学-临床神经学

CiteScore

4.60

自引率

3.60%

发文量

543

审稿时长

53 days

期刊介绍： This international, multidisciplinary journal covers all aspects of neuromuscular disorders in childhood and adult life (including the muscular dystrophies, spinal muscular atrophies, hereditary neuropathies, congenital myopathies, myasthenias, myotonic syndromes, metabolic myopathies and inflammatory myopathies). The Editors welcome original articles from all areas of the field: • Clinical aspects, such as new clinical entities, case studies of interest, treatment, management and rehabilitation (including biomechanics, orthotic design and surgery). • Basic scientific studies of relevance to the clinical syndromes, including advances in the fields of molecular biology and genetics. • Studies of animal models relevant to the human diseases. The journal is aimed at a wide range of clinicians, pathologists, associated paramedical professionals and clinical and basic scientists with an interest in the study of neuromuscular disorders.