Pontospinal control of nociception via a negative feedback loop.

IF 14.7 1区医学 Q1 NEUROSCIENCES

Neuron Pub Date : 2025-06-04 DOI:10.1016/j.neuron.2025.05.007

Andrew D Vigotsky, Adrien Tassou, Grégory Scherrer

引用次数: 0

Abstract

The nociceptive apparatus has the remarkable ability to regulate itself by amplifying and attenuating nociception and thus pain in a context-dependent way. In this issue of Neuron, Li et al.¹ identified a subpopulation of pontospinal projection neurons that dampen nociception in mice.

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通过负反馈回路的桥脊控制伤害感觉。

痛觉器官具有显著的自我调节能力，通过放大和减弱痛觉，从而以一种情境依赖的方式调节疼痛。在这一期的《神经元》杂志上，Li等人1发现了一个抑制小鼠伤害感觉的桥脊投射神经元亚群。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Neuron 医学-神经科学

CiteScore

24.50

自引率

3.10%

发文量

382

审稿时长

1 months

期刊介绍： Established as a highly influential journal in neuroscience, Neuron is widely relied upon in the field. The editors adopt interdisciplinary strategies, integrating biophysical, cellular, developmental, and molecular approaches alongside a systems approach to sensory, motor, and higher-order cognitive functions. Serving as a premier intellectual forum, Neuron holds a prominent position in the entire neuroscience community.