{"title":"mSphere of Influence: Adapting new models for studying <i>Toxoplasma gondii</i> gut interactions.","authors":"Carlos J Ramírez-Flores","doi":"10.1128/msphere.00211-25","DOIUrl":null,"url":null,"abstract":"<p><p>Carlos J. Ramírez-Flores works in the field of parasitology, focusing on how <i>Toxoplasma gondii</i> crosses host barriers. In this mSphere of Influence article, he reflects on how three papers-by Shim, Kim, and Gregg-built on Dubey's foundational mouse work to reshape his view of the parasite's earliest intestinal events and to inspire his use of gut-on-chip platforms.</p>","PeriodicalId":19052,"journal":{"name":"mSphere","volume":" ","pages":"e0021125"},"PeriodicalIF":3.7000,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188729/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"mSphere","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1128/msphere.00211-25","RegionNum":2,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/6/6 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"MICROBIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Carlos J. Ramírez-Flores works in the field of parasitology, focusing on how Toxoplasma gondii crosses host barriers. In this mSphere of Influence article, he reflects on how three papers-by Shim, Kim, and Gregg-built on Dubey's foundational mouse work to reshape his view of the parasite's earliest intestinal events and to inspire his use of gut-on-chip platforms.
Carlos J. Ramírez-Flores在寄生虫学领域工作,主要研究弓形虫如何跨越宿主屏障。在这篇mSphere of Influence的文章中,他回顾了三篇论文——由Shim, Kim和gregg——是如何在Dubey的基础小鼠研究的基础上,重塑了他对寄生虫最早的肠道事件的看法,并启发了他对肠道芯片平台的使用。
期刊介绍:
mSphere™ is a multi-disciplinary open-access journal that will focus on rapid publication of fundamental contributions to our understanding of microbiology. Its scope will reflect the immense range of fields within the microbial sciences, creating new opportunities for researchers to share findings that are transforming our understanding of human health and disease, ecosystems, neuroscience, agriculture, energy production, climate change, evolution, biogeochemical cycling, and food and drug production. Submissions will be encouraged of all high-quality work that makes fundamental contributions to our understanding of microbiology. mSphere™ will provide streamlined decisions, while carrying on ASM''s tradition for rigorous peer review.