jdispatcher-viewers: interactive visualizations of sequence similarity search results and domain predictions.

IF 2.4 Q2 MATHEMATICAL & COMPUTATIONAL BIOLOGY
Bioinformatics advances Pub Date : 2025-05-23 eCollection Date: 2025-01-01 DOI:10.1093/bioadv/vbaf122
Fábio Madeira, Joonheung Lee, Nandana Madhusoodanan, Alberto Eusebi, Ania Niewielska, Sarah Butcher
{"title":"jdispatcher-viewers: interactive visualizations of sequence similarity search results and domain predictions.","authors":"Fábio Madeira, Joonheung Lee, Nandana Madhusoodanan, Alberto Eusebi, Ania Niewielska, Sarah Butcher","doi":"10.1093/bioadv/vbaf122","DOIUrl":null,"url":null,"abstract":"<p><strong>Motivation: </strong>Biological visualization is an important technique for researchers to make sense of complex biological data. Functional prediction and the discovery of novel proteins remain central objectives in biology, as they provide insights into molecular mechanisms with significant applications in health and disease. Visualizing sequence similarity search results and domain predictions is essential for exploring protein function, identifying conserved elements, and drawing meaningful connections between sequences, ultimately accelerating discovery.</p><p><strong>Results: </strong>The new website for the EMBL-EBI Job Dispatcher bioinformatics tools framework, was released in 2023. Along with improvements and new features, the website has since integrated interactive visualizations designed to aid researchers further and enrich the user experience. Here, we describe jdispatcher-viewers, a library for the interactive visualization of sequence similarity search results from BLAST and FASTA, and interactive visualizations of domain predictions and annotations provided by InterPro.</p><p><strong>Availability and implementation: </strong>The jdispatcher-viewers library and documentation which includes a demo webpage are available from https://github.com/ebi-jdispatcher/jdispatcher-viewers. Interactive visualizations provided among the result pages of sequence similarity search tools in Job Dispatcher have been implemented using jdispatcher-viewers, and are available at https://www.ebi.ac.uk/jdispatcher/sss. The library is distributed under the Apache 2.0 license.</p>","PeriodicalId":72368,"journal":{"name":"Bioinformatics advances","volume":"5 1","pages":"vbaf122"},"PeriodicalIF":2.4000,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12133269/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bioinformatics advances","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/bioadv/vbaf122","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"MATHEMATICAL & COMPUTATIONAL BIOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Motivation: Biological visualization is an important technique for researchers to make sense of complex biological data. Functional prediction and the discovery of novel proteins remain central objectives in biology, as they provide insights into molecular mechanisms with significant applications in health and disease. Visualizing sequence similarity search results and domain predictions is essential for exploring protein function, identifying conserved elements, and drawing meaningful connections between sequences, ultimately accelerating discovery.

Results: The new website for the EMBL-EBI Job Dispatcher bioinformatics tools framework, was released in 2023. Along with improvements and new features, the website has since integrated interactive visualizations designed to aid researchers further and enrich the user experience. Here, we describe jdispatcher-viewers, a library for the interactive visualization of sequence similarity search results from BLAST and FASTA, and interactive visualizations of domain predictions and annotations provided by InterPro.

Availability and implementation: The jdispatcher-viewers library and documentation which includes a demo webpage are available from https://github.com/ebi-jdispatcher/jdispatcher-viewers. Interactive visualizations provided among the result pages of sequence similarity search tools in Job Dispatcher have been implemented using jdispatcher-viewers, and are available at https://www.ebi.ac.uk/jdispatcher/sss. The library is distributed under the Apache 2.0 license.

jdispatcher-viewer:序列相似性搜索结果和领域预测的交互式可视化。
动机:生物可视化是研究人员理解复杂生物数据的重要技术。功能预测和新蛋白质的发现仍然是生物学的中心目标,因为它们提供了对健康和疾病方面具有重要应用的分子机制的见解。可视化序列相似性搜索结果和结构域预测对于探索蛋白质功能,识别保守元件,绘制序列之间有意义的联系,最终加速发现是必不可少的。结果:EMBL-EBI Job Dispatcher生物信息学工具框架的新网站于2023年发布。除了改进和新功能之外,该网站还集成了交互式可视化,旨在进一步帮助研究人员并丰富用户体验。在这里,我们描述了jdispatcher-viewer,一个用于BLAST和FASTA序列相似性搜索结果交互式可视化的库,以及InterPro提供的领域预测和注释的交互式可视化。可用性和实现:可以从https://github.com/ebi-jdispatcher/jdispatcher-viewers获得jdispatcher-viewer库和文档,其中包括一个演示网页。Job Dispatcher中序列相似性搜索工具的结果页之间提供的交互式可视化已经使用jdispatcher-viewer实现,可以在https://www.ebi.ac.uk/jdispatcher/sss上获得。该库是在Apache 2.0许可下发布的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
1.60
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信