The bibliometric analysis of research on traditional Chinese medicine regulating gut microbiota for cancer treatment from 2014 to 2024.

IF 2.5 3区生物学

Hereditas Pub Date : 2025-06-03 DOI:10.1186/s41065-025-00456-x

Youfeng Lei, Yueqin Shan, Danfeng Zhou, Chunyan Chen

{"title":"The bibliometric analysis of research on traditional Chinese medicine regulating gut microbiota for cancer treatment from 2014 to 2024.","authors":"Youfeng Lei, Yueqin Shan, Danfeng Zhou, Chunyan Chen","doi":"10.1186/s41065-025-00456-x","DOIUrl":null,"url":null,"abstract":"Objective: The modulation of gut microbiota by Traditional Chinese Medicine (TCM) offers a promising approach to cancer treatment. However, a comprehensive bibliometric evaluation of this emerging field is lacking.Objective: This study aimed to systematically analyze global research trends, hotspots, and future directions related to TCM regulation of gut microbiota in cancer therapy from 2014 to 2024.Methods: Publications were retrieved from the Web of Science Core Collection. Bibliometric and visual analyses were conducted using VOSviewer and CiteSpace to examine publication trends, country and institutional collaborations, core authors and journals, keyword co-occurrence, and research frontiers.Results: A total of 340 relevant articles were identified. The number of publications increased significantly after 2018, indicating growing interest in this field. China dominated the research landscape, both in productivity and institutional collaboration. Core research hotspots included \"short-chain fatty acids,\" \"tumor microenvironment,\" \"apoptosis,\" and \"immune response.\" Thematic evolution analysis highlighted a shift from general gut microbiota research to precise molecular mechanisms and targeted regulation. Emerging topics such as \"metabolomics\" and \"immune checkpoint blockade\" suggest future directions.Conclusion: This study provides a comprehensive overview of the current research landscape on TCM-modulated gut microbiota in cancer treatment. By identifying core contributors, research hotspots, and frontiers, it offers valuable guidance for future investigations and interdisciplinary collaborations in this promising field.","PeriodicalId":12862,"journal":{"name":"Hereditas","volume":"162 1","pages":"94"},"PeriodicalIF":2.5000,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12131599/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Hereditas","FirstCategoryId":"99","ListUrlMain":"https://doi.org/10.1186/s41065-025-00456-x","RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

Abstract

Objective: The modulation of gut microbiota by Traditional Chinese Medicine (TCM) offers a promising approach to cancer treatment. However, a comprehensive bibliometric evaluation of this emerging field is lacking.

Objective: This study aimed to systematically analyze global research trends, hotspots, and future directions related to TCM regulation of gut microbiota in cancer therapy from 2014 to 2024.

Methods: Publications were retrieved from the Web of Science Core Collection. Bibliometric and visual analyses were conducted using VOSviewer and CiteSpace to examine publication trends, country and institutional collaborations, core authors and journals, keyword co-occurrence, and research frontiers.

Results: A total of 340 relevant articles were identified. The number of publications increased significantly after 2018, indicating growing interest in this field. China dominated the research landscape, both in productivity and institutional collaboration. Core research hotspots included "short-chain fatty acids," "tumor microenvironment," "apoptosis," and "immune response." Thematic evolution analysis highlighted a shift from general gut microbiota research to precise molecular mechanisms and targeted regulation. Emerging topics such as "metabolomics" and "immune checkpoint blockade" suggest future directions.

Conclusion: This study provides a comprehensive overview of the current research landscape on TCM-modulated gut microbiota in cancer treatment. By identifying core contributors, research hotspots, and frontiers, it offers valuable guidance for future investigations and interdisciplinary collaborations in this promising field.

查看原文本刊更多论文

2014 - 2024年中药调节肠道菌群治疗癌症研究的文献计量学分析

目的：中药调节肠道菌群为癌症治疗提供了一条有前景的途径。然而，对这一新兴领域缺乏全面的文献计量学评价。目的：本研究旨在系统分析2014 - 2024年中医药调控肠道菌群在癌症治疗中的全球研究趋势、热点及未来发展方向。方法：出版物从Web of Science Core Collection检索。使用VOSviewer和CiteSpace进行文献计量学和可视化分析，以检查出版趋势、国家和机构合作、核心作者和期刊、关键词共现和研究前沿。结果：共鉴定出相关文献340篇。2018年之后，出版物数量显著增加，表明人们对这一领域的兴趣日益浓厚。中国在研究领域占据主导地位，无论是在生产力方面还是在机构合作方面。核心研究热点包括“短链脂肪酸”、“肿瘤微环境”、“细胞凋亡”、“免疫应答”等。主题进化分析强调了从一般肠道微生物群研究到精确分子机制和靶向调控的转变。诸如“代谢组学”和“免疫检查点阻断”等新兴主题提示了未来的发展方向。结论：本研究对中医药调节肠道菌群在癌症治疗中的研究现状进行了全面概述。通过识别核心贡献者、研究热点和前沿，为这一前景广阔的领域的未来研究和跨学科合作提供了有价值的指导。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Hereditas Biochemistry, Genetics and Molecular Biology-Genetics

CiteScore

3.80

自引率

3.70%

发文量

期刊介绍： For almost a century, Hereditas has published original cutting-edge research and reviews. As the Official journal of the Mendelian Society of Lund, the journal welcomes research from across all areas of genetics and genomics. Topics of interest include human and medical genetics, animal and plant genetics, microbial genetics, agriculture and bioinformatics.