{"title":"Mapping the knowledge of epilepsy and Potassium Channels: A scientometric analysis in CiteSpace and VOSviewer","authors":"Zheng Li","doi":"10.1016/j.ibneur.2025.05.004","DOIUrl":null,"url":null,"abstract":"<div><div>Epilepsy is one of the most common neurological diseases. Studies have suggested that epileptic seizures are directly related to ion channel abnormalities in the central nervous system. Activation of potassium ion channels may lead to increased cell excitability and abnormal neuronal excitation. Over the past decade, significant progress has been achieved in understanding the potassium ion channel abnormalities related to epilepsy. To facilitate further research, in this paper, we adopted the bibliometrics method (based on Web of Science database) and used CiteSpace and VOSviewer to visualize literature in the field (Potassium Channels-related epilepsy) from 2010 to 2023. A total of 2415 original research and summary papers were included, and the basic situation, subject theme, and knowledge structure evolution were analyzed and discussed step by step from macro to micro perspectives.</div></div>","PeriodicalId":13195,"journal":{"name":"IBRO Neuroscience Reports","volume":"19 ","pages":"Pages 1-16"},"PeriodicalIF":2.0000,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"IBRO Neuroscience Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2667242125000703","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"NEUROSCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Epilepsy is one of the most common neurological diseases. Studies have suggested that epileptic seizures are directly related to ion channel abnormalities in the central nervous system. Activation of potassium ion channels may lead to increased cell excitability and abnormal neuronal excitation. Over the past decade, significant progress has been achieved in understanding the potassium ion channel abnormalities related to epilepsy. To facilitate further research, in this paper, we adopted the bibliometrics method (based on Web of Science database) and used CiteSpace and VOSviewer to visualize literature in the field (Potassium Channels-related epilepsy) from 2010 to 2023. A total of 2415 original research and summary papers were included, and the basic situation, subject theme, and knowledge structure evolution were analyzed and discussed step by step from macro to micro perspectives.
癫痫是最常见的神经系统疾病之一。研究表明,癫痫发作与中枢神经系统离子通道异常有直接关系。钾离子通道的激活可导致细胞兴奋性增加和神经元异常兴奋。在过去的十年中,在了解与癫痫相关的钾离子通道异常方面取得了重大进展。为了便于进一步研究,本文采用文献计量学方法(基于Web of Science数据库),利用CiteSpace和VOSviewer对2010 - 2023年钾通道相关癫痫领域的文献进行可视化。共收录原创研究和总结论文2415篇,从宏观到微观的角度对基本情况、课题主题、知识结构演变等进行了逐级分析和探讨。