{"title":"Are Astrocytes the Pressure-Reservoirs of Lactate in the Brain?","authors":"Sergey Kasparov","doi":"10.1016/j.cmet.2015.11.001","DOIUrl":null,"url":null,"abstract":"<p><p>The role of lactate in the brain has been controversial. In this issue, Mächler et al. (2015) present data from in vivo experiments suggesting that there is a downward gradient of lactate in the brain. They provide a mechanistic basis for the proposed export of lactate from astrocytes to neurons.</p>","PeriodicalId":93927,"journal":{"name":"Cell metabolism","volume":"23 1","pages":"1-2"},"PeriodicalIF":0.0000,"publicationDate":"2016-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cell metabolism","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.cmet.2015.11.001","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2015/11/19 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
The role of lactate in the brain has been controversial. In this issue, Mächler et al. (2015) present data from in vivo experiments suggesting that there is a downward gradient of lactate in the brain. They provide a mechanistic basis for the proposed export of lactate from astrocytes to neurons.
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