Celiac Disease and Incident Dupuytren's Contracture: A Matched Nationwide Cohort Analysis.

IF 3.2 2区医学 Q1 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Clinical Epidemiology Pub Date : 2025-05-24 eCollection Date: 2025-01-01 DOI:10.2147/CLEP.S518939

Shuai Yuan, Dominic Furniss, Susanna C Larsson, Daniel A Leffler, Jonas F Ludvigsson

引用次数: 0

Abstract

This study explored the association between celiac disease (CeD) and Dupuytren's contracture (DC) using data from the Swedish ESPRESSO cohort. We analyzed 49,699 CeD patients and 245,267 matched controls, identifying 1420 incident DC cases. CeD patients had a 1.21-fold increased risk of DC compared to controls, with a more pronounced risk in women and older individuals. Further research is needed to understand the underlying mechanisms of this relationship.

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乳糜泻和Dupuytren's挛缩：一项匹配的全国队列分析。

本研究利用来自瑞典ESPRESSO队列的数据探讨了乳糜泻（CeD）和Dupuytren's挛缩（DC）之间的关系。我们分析了49,699例CeD患者和245,267例匹配对照，确定了1420例DC病例。与对照组相比，CeD患者发生DC的风险增加了1.21倍，其中女性和老年人的风险更明显。需要进一步的研究来了解这种关系的潜在机制。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Epidemiology Medicine-Epidemiology

CiteScore

6.30

自引率

5.10%

发文量

169

审稿时长

16 weeks

期刊介绍： Clinical Epidemiology is an international, peer reviewed, open access journal. Clinical Epidemiology focuses on the application of epidemiological principles and questions relating to patients and clinical care in terms of prevention, diagnosis, prognosis, and treatment. Clinical Epidemiology welcomes papers covering these topics in form of original research and systematic reviews. Clinical Epidemiology has a special interest in international electronic medical patient records and other routine health care data, especially as applied to safety of medical interventions, clinical utility of diagnostic procedures, understanding short- and long-term clinical course of diseases, clinical epidemiological and biostatistical methods, and systematic reviews. When considering submission of a paper utilizing publicly-available data, authors should ensure that such studies add significantly to the body of knowledge and that they use appropriate validated methods for identifying health outcomes. The journal has launched special series describing existing data sources for clinical epidemiology, international health care systems and validation studies of algorithms based on databases and registries.