Single-Use Technology Today - A Cornucopia of Applications.

Abstract

Whether for classic biologics or advanced therapy medicinal products (ATMPs), laboratory applications, small-scale or large-scale productions, single-use technology (SUT), and its associated consumables are used everywhere. The advantages of deploying SUTs are well known. Wherever a single-use solution is available, it is tested and ultimately used. Based on milestones in the development of single-use systems and single-use platform technologies, this article provides an up-to-date overview of products available on the market and their manufacturers/suppliers. It also discusses process examples with SUTs, design options and configurations of single-use facilities and Switzerland's pioneering role in the development and implementation of SUTs. In addition, the authors show that SUT has already been established beyond the biopharmaceutical sector.