Mechanisms of heme transport in the mitochondria.

IF 3.8 3区 生物学 Q2 BIOCHEMISTRY & MOLECULAR BIOLOGY
Saieeda Fabia Ali, Adrianna E White, Amy Medlock, Oleh Khalimonchuk
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引用次数: 0

Abstract

Heme is a vital but highly reactive compound that is synthesized in mitochondria and subsequently distributed to a variety of subcellular compartments for utilization. The transport of heme is essential for normal cellular metabolism, growth, and development. Despite the vital importance of heme transport within the cell, data are lacking about how newly synthesized heme is shuttled within the mitochondrion or exported from the organelle. Here, we briefly summarize current knowledge about the process of mitochondrial heme distribution and discuss the current unresolved questions pertinent to this process.

线粒体中血红素运输的机制。
血红素是一种重要的高活性化合物,在线粒体中合成,随后分布到各种亚细胞区室进行利用。血红素的运输是正常细胞代谢、生长和发育所必需的。尽管血红素在细胞内的运输至关重要,但关于新合成的血红素如何在线粒体内穿梭或从细胞器输出的数据缺乏。在这里,我们简要地总结了目前关于线粒体血红素分布过程的知识,并讨论了目前与此过程相关的未解决问题。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Biochemical Society transactions
Biochemical Society transactions 生物-生化与分子生物学
CiteScore
7.80
自引率
0.00%
发文量
351
审稿时长
3-6 weeks
期刊介绍: Biochemical Society Transactions is the reviews journal of the Biochemical Society. Publishing concise reviews written by experts in the field, providing a timely snapshot of the latest developments across all areas of the molecular and cellular biosciences. Elevating our authors’ ideas and expertise, each review includes a perspectives section where authors offer comment on the latest advances, a glimpse of future challenges and highlighting the importance of associated research areas in far broader contexts.
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