Yu Xie, Chenrui Zhang, Mingchi Ma, Ziqian Yin, Liqian Chen, Yimiao Yang, Shuang Wu, Yuanteng Fan, Yan Xu, Dan He
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引用次数: 0
Abstract
Purpose
Human Herpesvirus 6 (HHV-6) infections are primarily observed in immunocompromised individuals, such as those with acquired immunodeficiency syndrome or organ transplant recipients. However, its role as a pathogen in immunocompetent adults remains debated. We aimed to explore the clinical significance of HHV-6 in immunocompetent individuals by presenting a case of HHV-6-associated meningitis with concurrent lymphadenitis.
Method
We describe a case of an immunocompetent adult presenting with recurrent fever and headaches.
Finding
Diagnostic evaluations included next-generation sequencing analysis identified HHV-6 in both cerebrospinal fluid specimens and lymphoid tissue samples. The patient demonstrated complete clinical resolution following a 14-day course of ganciclovir therapy.
Conclusion
This case underscores the need to consider HHV-6 infection in immunocompetent adults presenting with meningitis of unknown etiology. Early detection and targeted antiviral therapy may lead to favorable clinical outcomes
期刊介绍：
Brain and Behavior is supported by other journals published by Wiley, including a number of society-owned journals. The journals listed below support Brain and Behavior and participate in the Manuscript Transfer Program by referring articles of suitable quality and offering authors the option to have their paper, with any peer review reports, automatically transferred to Brain and Behavior.
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