[Efficacy of Scalp Cooling Therapy for Hair Loss Prevention and Recovery in Patients with Breast Cancer Receiving Chemotherapy at Our Hospital].

Abstract

We herein report the hair loss and recovery rates of patients treated with scalp cooling therapy at our hospital. Overall, 14 Japanese women with breast cancer who were scheduled to undergo chemotherapy and who used the Paxman Scalp Cooling SystemTM between May 2022 and May 2023 participated in our study. We retrospectively evaluated the efficacy of the scalp cooling therapy in preventing hair loss. We also assessed the extent of hair recovery at 1, 3, 6, and 12 months after chemotherapy using the scalp cooling therapy. Data were evaluated using the Dean scale. Post-chemotherapy, 8 patients (57.1%)experienced Grade 4 hair loss(defined as hair loss of >75%). No statistically significant difference was observed. A month after chemotherapy ended, the number of patients with Grade 4 hair loss reduced to 2/14(14.3%). No patient experienced Grade 4 hair loss after 3 months. By 6 months, all patients had recovered their pre-treatment hair volume. One year after chemotherapy, hair volume was sufficiently preserved. Our data indicate that scalp cooling during chemotherapy can reduce hair loss and accelerate hair regrowth.