[Neurophysiology of psychiatric disorders: building a national high-density electroencephalography platform].

IF 0.6 4区医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL

M S-medecine Sciences Pub Date : 2025-05-01 Epub Date: 2025-05-26 DOI:10.1051/medsci/2025076

Anton Iftimovici, Mahmoud Hassan, David M Alexander, Laura Dugué, Martine Gavaret, Renaud Jardri, Aline Lefebvre

引用次数: 0

Abstract

The PEPR PROPSY EEG-MIND project aims to develop transdiagnostic EEG biomarkers for psychiatric disorders, such as autism, schizophrenia and mood disorders. It combines experimental tasks (rest, mismatch negativity, sensori-motor, audiovisual) to study brain connectivity and neurophysiological abnormalities at the individual level. The aim is to identify markers of oscillatory anomalies, excitation/inhibition ratio, wave propagation and connectivity, and then apply normative models to highlight specific neurocognitive profiles associated to the underlying neurophysiology, which could benefit from personalized targeted approaches such as neuromodulation.

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[精神障碍神经生理学：构建国家高密度脑电图平台]。

PEPR PROPSY EEG- mind项目旨在开发精神疾病的跨诊断脑电图生物标志物，如自闭症、精神分裂症和情绪障碍。它结合了实验任务（休息、错配消极、感觉-运动、视听）来研究个体水平上的大脑连接和神经生理异常。目的是识别振荡异常、兴奋/抑制比、波传播和连通性的标记，然后应用规范模型来突出与潜在神经生理学相关的特定神经认知特征，这可能受益于个性化的定向方法，如神经调节。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

M S-medecine Sciences 医学-医学：研究与实验

CiteScore

0.80

自引率

14.30%

发文量

182

审稿时长

4-8 weeks

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