RETRACTION: Evaluation of Anticancer Effects of Cerium Oxide Nanoparticles on Mouse Fibrosarcoma Cell Line

IF 4.5 2区 生物学 Q2 CELL BIOLOGY
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引用次数: 0

Abstract

RETRACTION: E. Nourmohammadi, H. Khoshdel–Sarkarizi, R. Nedaeinia, H. R. Sadeghnia, L. Hasanzadeh, M. Darroudi and R. K. Oskuee, “Evaluation of Anticancer Effects of Cerium Oxide Nanoparticles on Mouse Fibrosarcoma Cell Line,” Journal of Cellular Physiology 234, no. 4 (2019): 4987–4996, https://doi.org/10.1002/jcp.27303.

The above article, published online on 06 September 2018 in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editor-in-Chief, Robert Heath; and Wiley Periodicals LLC. The retraction has been agreed upon following an investigation into concerns raised by a third party. The investigation revealed duplication between the L929-Control flow cytometry plot and the L929-Conc30 plot shown in Figure 7b. Furthermore, duplications were identified between the Conc 30 BAX western blot band presented in Figures 9a and the Control BAX western blot band in Figure 9b. These two figures represent different cell lines. An additional duplication was observed between the Control BCL2 band and the Conc 60 BAX band in Figure 9a. The authors provided an explanation and some data, but this was not deemed sufficient. The editors consider the results and conclusions from this study to be substantially compromised. The authors disagree with the retraction.

撤回:氧化铈纳米颗粒对小鼠纤维肉瘤细胞系抗癌作用的评价
引用本文:E. Nourmohammadi, H. Khoshdel-Sarkarizi, R. nedainia, H. R. Sadeghnia, L. Hasanzadeh, M. Darroudi, R. K. Oskuee,“氧化铈纳米颗粒对小鼠纤维肉瘤细胞的抗癌作用的评价”,细胞生理学杂志,第234期。4 (2019): 4987-4996, https://doi.org/10.1002/jcp.27303.The上述文章于2018年9月6日在线发表在Wiley在线图书馆(wileyonlinelibrary.com)上,经主编Robert Heath同意撤回;和Wiley期刊有限责任公司。在对第三方提出的问题进行调查后,双方同意撤回论文。研究发现L929-Control流式细胞术图与图7b所示的L929-Conc30图之间存在重复。此外,图9a所示的Conc 30 BAX western blot条带与图9b所示的Control BAX western blot条带之间存在重复。这两个图代表不同的细胞系。在图9a中,在Control BCL2条带和Conc 60 BAX条带之间观察到额外的重复。作者提供了一个解释和一些数据,但这被认为是不够的。编辑认为本研究的结果和结论存在很大的缺陷。作者不同意撤稿。
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来源期刊
CiteScore
14.70
自引率
0.00%
发文量
256
审稿时长
1 months
期刊介绍: The Journal of Cellular Physiology publishes reports of high biological significance in areas of eukaryotic cell biology and physiology, focusing on those articles that adopt a molecular mechanistic approach to investigate cell structure and function. There is appreciation for the application of cellular, biochemical, molecular and in vivo genetic approaches, as well as the power of genomics, proteomics, bioinformatics and systems biology. In particular, the Journal encourages submission of high-interest papers investigating the genetic and epigenetic regulation of proliferation and phenotype as well as cell fate and lineage commitment by growth factors, cytokines and their cognate receptors and signal transduction pathways that influence the expression, integration and activities of these physiological mediators. Similarly, the Journal encourages submission of manuscripts exploring the regulation of growth and differentiation by cell adhesion molecules in addition to the interplay between these processes and those induced by growth factors and cytokines. Studies on the genes and processes that regulate cell cycle progression and phase transition in eukaryotic cells, and the mechanisms that determine whether cells enter quiescence, proliferate or undergo apoptosis are also welcomed. Submission of papers that address contributions of the extracellular matrix to cellular phenotypes and physiological control as well as regulatory mechanisms governing fertilization, embryogenesis, gametogenesis, cell fate, lineage commitment, differentiation, development and dynamic parameters of cell motility are encouraged. Finally, the investigation of stem cells and changes that differentiate cancer cells from normal cells including studies on the properties and functions of oncogenes and tumor suppressor genes will remain as one of the major interests of the Journal.
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