Recent advances in metastatic bone disease

Abstract

Metastatic bone disease (MBD) is a common sequela of malignancy and can lead to significant morbidity on patients. Systemic medical therapies and oncology surgery have greatly enhanced cancer survival rates over recent decades. Orthopaedic surgeons occupy a key position within the multidisciplinary team and coordinate surgical care for bone metastases where appropriate. This review describes the investigations for, and management of, patients with metastases to the appendicular skeleton. National British Orthopaedic Association Standard (BOASt) guidelines exist to help orthopaedic clinicians and departments optimize patient care. We outline and illustrate the freely available OPTIModel app, which is an innovative, straightforward and useful tool for prognostic evaluation and suggestion of loco-regional treatment options for patients with symptomatic long bone metastases.