Rooted in regulation: MicroRNAs as gardeners of the Purkinje cell dendritic arbor.

IF 15 1区医学 Q1 NEUROSCIENCES

Neuron Pub Date : 2025-05-21 DOI:10.1016/j.neuron.2025.04.016

Cheryl Brandenburg, Roy V Sillitoe

引用次数: 0

Abstract

Zolboot et al.¹ developed tools to manipulate and map microRNA function in cerebellar Purkinje cells with temporal precision, revealing key roles in dendritic development and circuit connectivity. Their approach provides insight into microRNA-mediated regulation of neurodevelopment in sparse neuronal populations.

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根植于调控：作为浦肯野细胞树突乔木园丁的microrna。

Zolboot等人开发了工具来操纵和绘制小脑浦肯野细胞中的microRNA功能，具有时间精度，揭示了树突发育和电路连接的关键作用。他们的方法提供了对稀疏神经元群体中微rna介导的神经发育调控的见解。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Neuron 医学-神经科学

CiteScore

24.50

自引率

3.10%

发文量

382

审稿时长

1 months

期刊介绍： Established as a highly influential journal in neuroscience, Neuron is widely relied upon in the field. The editors adopt interdisciplinary strategies, integrating biophysical, cellular, developmental, and molecular approaches alongside a systems approach to sensory, motor, and higher-order cognitive functions. Serving as a premier intellectual forum, Neuron holds a prominent position in the entire neuroscience community.