A polymicrobial perspective into the ecological role of Enterococcus faecalis in dental root canal infections.

IF 9.2 1区生物学 Q1 BIOTECHNOLOGY & APPLIED MICROBIOLOGY

npj Biofilms and Microbiomes Pub Date : 2025-05-22 DOI:10.1038/s41522-025-00722-w

Ana Parga, Jade Mattu, Georgios N Belibasakis, Kimberly A Kline, Julian G Leprince, Daniel Manoil

引用次数: 0

Abstract

Enterococcus faecalis, a non-oral nosocomial pathogen, intriguingly ranks among the most frequently retrieved species from polymicrobial infections of dental root canals. This review integrates findings from the latest omics approaches, alongside emerging evidence of E. faecalis interactions within oral polymicrobial communities, to refine our understanding of its role in these infections. Herein, E. faecalis emerges as an ecologically invasive species and a catalyst of the pathogenicity of entire communities.

查看原文本刊更多论文

粪肠球菌在牙根管感染中的生态学作用的多微生物视角。

粪肠球菌（Enterococcus faecalis）是一种非口腔的医院病原菌，有趣的是，它是最常从牙根管多微生物感染中检索到的物种之一。本综述整合了最新组学方法的发现，以及口腔多微生物群落中粪肠杆菌相互作用的新证据，以完善我们对其在这些感染中的作用的理解。因此，粪肠球菌是一种生态入侵物种，也是整个群落致病性的催化剂。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

npj Biofilms and Microbiomes Immunology and Microbiology-Microbiology

CiteScore

12.10

自引率

3.30%

发文量

审稿时长

9 weeks

期刊介绍： npj Biofilms and Microbiomes is a comprehensive platform that promotes research on biofilms and microbiomes across various scientific disciplines. The journal facilitates cross-disciplinary discussions to enhance our understanding of the biology, ecology, and communal functions of biofilms, populations, and communities. It also focuses on applications in the medical, environmental, and engineering domains. The scope of the journal encompasses all aspects of the field, ranging from cell-cell communication and single cell interactions to the microbiomes of humans, animals, plants, and natural and built environments. The journal also welcomes research on the virome, phageome, mycome, and fungome. It publishes both applied science and theoretical work. As an open access and interdisciplinary journal, its primary goal is to publish significant scientific advancements in microbial biofilms and microbiomes. The journal enables discussions that span multiple disciplines and contributes to our understanding of the social behavior of microbial biofilm populations and communities, and their impact on life, human health, and the environment.