Effects of degradation-associated polypropylene particles in the surrounding tissue after surgical mesh implantation

IF 12.1 1区医学 Q1 UROLOGY & NEPHROLOGY

Nature Reviews Urology Pub Date : 2025-05-23 DOI:10.1038/s41585-025-01046-2

Nicholas T. H. Farr, Pascal Achenbach, Karl-Dietrich Sievert

引用次数: 0

Abstract

Evidence of polypropylene mesh degradation has revealed particle accumulation in surrounding tissues, raising concerns about potential local and systemic immune responses. Associations between polypropylene degradation and autoimmune/autoinflammatory syndrome induced by adjuvants-like symptoms have been made, and vigilant clinical assessment is important, especially in patients with a predisposition for allergy or autoimmune diseases.

Abstract Image

查看原文本刊更多论文

手术补片植入后周围组织中降解相关聚丙烯颗粒的影响

聚丙烯网片降解的证据显示颗粒在周围组织中积聚，引起对潜在的局部和全身免疫反应的关注。聚丙烯降解与佐剂样症状引起的自身免疫/自身炎症综合征之间存在关联，警惕的临床评估很重要，特别是对过敏或自身免疫性疾病易感性的患者。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Nature Reviews Urology 医学-泌尿学与肾脏学

CiteScore

12.50

自引率

2.60%

发文量

123

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Urology is part of the Nature Reviews portfolio of journals.Nature Reviews' basic, translational and clinical content is written by internationally renowned basic and clinical academics and researchers. This journal targeted readers in the biological and medical sciences, from the postgraduate level upwards, aiming to be accessible to professionals in any biological or medical discipline. The journal features authoritative In-depth Reviews providing up-to-date information on topics within a field's history and development. Perspectives, News & Views articles, and the Research Highlights section offer topical discussions and opinions, filtering primary research from various medical journals. Covering a wide range of subjects, including andrology, urologic oncology, and imaging, Nature Reviews provides valuable insights for practitioners, researchers, and academics within urology and related fields.