TEMPO-Mediated Polyyne Cyclization

IF 5 1区化学 Q1 CHEMISTRY, ORGANIC

Organic Letters Pub Date : 2025-05-22 DOI:10.1021/acs.orglett.5c00651

Qiaofeng Liang, Ying Xia, Chenlong Zhu, Bingfeng Sun

引用次数: 0

Abstract

In this work, we report the cyclization of sulfur-linked tetraynes under 2,2,6,6-tetramethylpiperidine 1-oxyl (TEMPO) radical conditions, leading to the formation of novel pentadehydro-Diels–Alder-type addition products. Through this study, we expand the scope of radical-mediated cyclization reactions of polyyne compounds. The results offer new opportunities for the development of radical-based synthetic methodologies.

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tempo介导的聚乙烯环化

在这项工作中，我们报道了在2,2,6,6-四甲基哌啶1-氧（TEMPO）自由基条件下，硫连接的四烷环化，导致新的五氢- diols - alder型加成产物的形成。通过本研究，我们扩大了自由基介导的聚乙烯化合物环化反应的范围。这些结果为基基合成方法的发展提供了新的机会。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Organic Letters 化学-有机化学

CiteScore

9.30

自引率

11.50%

发文量

1607

审稿时长

1.5 months

期刊介绍： Organic Letters invites original reports of fundamental research in all branches of the theory and practice of organic, physical organic, organometallic,medicinal, and bioorganic chemistry. Organic Letters provides rapid disclosure of the key elements of significant studies that are of interest to a large portion of the organic community. In selecting manuscripts for publication, the Editors place emphasis on the originality, quality and wide interest of the work. Authors should provide enough background information to place the new disclosure in context and to justify the rapid publication format. Back-to-back Letters will be considered. Full details should be reserved for an Article, which should appear in due course.