Gut microbiota and ovarian diseases: a new therapeutic perspective.

IF 3.8 3区医学 Q1 REPRODUCTIVE BIOLOGY

Journal of Ovarian Research Pub Date : 2025-05-21 DOI:10.1186/s13048-025-01684-5

Shan Ju, Zhen Yang Kang, Li Ya Yang, Yong Jun Xia, Yi Ming Guo, Sui Li, Hongli Yan, Ming Kang Qi, Hui Ping Wang, Lian Zhong

引用次数: 0

Abstract

The gut microbiota is a complex community of microorganisms that inhabit the human gastrointestinal tract, helping to maintain the ecological balance of the body's internal and external environments. Disruptions in the composition and diversity of gut microbiota, as well as changes in their metabolic functions, can link to the development and severity of conditions such as premature ovarian insufficiency, polycystic ovary syndrome, and ovarian tumors. This article thoroughly reviews recent research on the connection between gut microbiota and ovarian diseases, providing fresh perspectives on their prevention, pathogenesis, and treatment.

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肠道微生物群与卵巢疾病：一个新的治疗视角。

肠道菌群是一个复杂的微生物群落，栖息在人体胃肠道中，帮助维持人体内外环境的生态平衡。肠道微生物群组成和多样性的破坏，以及它们代谢功能的改变，可能与卵巢功能不全、多囊卵巢综合征和卵巢肿瘤等疾病的发展和严重程度有关。本文综述了近年来肠道微生物群与卵巢疾病之间关系的研究进展，为卵巢疾病的预防、发病机制和治疗提供了新的视角。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Ovarian Research REPRODUCTIVE BIOLOGY-

CiteScore

6.20

自引率

2.50%

发文量

125

审稿时长

>12 weeks

期刊介绍： Journal of Ovarian Research is an open access, peer reviewed, online journal that aims to provide a forum for high-quality basic and clinical research on ovarian function, abnormalities, and cancer. The journal focuses on research that provides new insights into ovarian functions as well as prevention and treatment of diseases afflicting the organ. Topical areas include, but are not restricted to: Ovary development, hormone secretion and regulation Follicle growth and ovulation Infertility and Polycystic ovarian syndrome Regulation of pituitary and other biological functions by ovarian hormones Ovarian cancer, its prevention, diagnosis and treatment Drug development and screening Role of stem cells in ovary development and function.