Embryonic Stem Cell Research Oversight Committees: A Model for Oversight of Innovative Research?

IF 3.7 4区生物学 Q2 GENETICS & HEREDITY

CRISPR Journal Pub Date : 2025-05-21 DOI:10.1089/crispr.2025.0056

Robert D Truog

引用次数: 0

Abstract

Ethically challenging areas of research raise the question of how science can proceed in an ethically reflective and careful way and what role ethical deliberative bodies at the local level play in this. Important lessons can be drawn from the experience of Embryonic Stem Cell Research Oversight Committees (ESCROs). ESCROs have evolved as reflective spaces in response to changes in the science, including research on "humanization" of experimental rodents, embryogenesis, and developing human germ cells. Institutional efforts can contribute to broader goals of open and democratic deliberation.

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胚胎干细胞研究监督委员会：创新研究的监督模式？

具有伦理挑战的研究领域提出了这样一个问题：科学如何才能以伦理反思和谨慎的方式进行，以及地方层面的伦理审议机构在这方面发挥什么作用。可以从胚胎干细胞研究监督委员会（ESCROs）的经验中吸取重要的教训。escro已经发展成为一个反思空间，以应对科学的变化，包括实验啮齿动物的“人性化”研究，胚胎发生和发育人类生殖细胞。体制上的努力有助于实现公开和民主审议的更广泛目标。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

CRISPR Journal Biochemistry, Genetics and Molecular Biology-Biotechnology

CiteScore

6.30

自引率

2.70%

发文量

期刊介绍： In recognition of this extraordinary scientific and technological era, Mary Ann Liebert, Inc., publishers recently announced the creation of The CRISPR Journal -- an international, multidisciplinary peer-reviewed journal publishing outstanding research on the myriad applications and underlying technology of CRISPR. Debuting in 2018, The CRISPR Journal will be published online and in print with flexible open access options, providing a high-profile venue for groundbreaking research, as well as lively and provocative commentary, analysis, and debate. The CRISPR Journal adds an exciting and dynamic component to the Mary Ann Liebert, Inc. portfolio, which includes GEN (Genetic Engineering & Biotechnology News) and more than 80 leading peer-reviewed journals.