{"title":"Accidental intravenous overdose of meloxicam in a Cape Vulture <i>(Gyps coprotheres)</i>.","authors":"B A T Gazendam, K N Koeppel","doi":"10.36303/JSAVA.640","DOIUrl":null,"url":null,"abstract":"<p><p>Many species of vulture are under threat from man-made inventions; this has led to wounded and sick vultures presenting for veterinary treatment and in need of pain management. Following the devastating effect of diclofenac on vultures in South Asia, meloxicam was found to be very safe for vultures, as a treatment as well as through ingestion of meat from treated animals. Many studies investigated the safety of meloxicam, and all found it to be safe up to 2 mg/kg, which was deemed the maximum likely exposure through treated carcasses. All studies exposed the birds either through oral dosing, treated meat or intramuscular administration, no instances of toxicity where recorded and all birds remained healthy. In this case the bird was exposed to a single dose of 2 mg/kg, intravenously, with no signs of toxicity. This appears to be the first recorded instance of accidental intravenous administration of meloxicam in a vulture.</p>","PeriodicalId":17467,"journal":{"name":"Journal of the South African Veterinary Association","volume":" ","pages":""},"PeriodicalIF":0.5000,"publicationDate":"2025-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of the South African Veterinary Association","FirstCategoryId":"97","ListUrlMain":"https://doi.org/10.36303/JSAVA.640","RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"VETERINARY SCIENCES","Score":null,"Total":0}
引用次数: 0
Abstract
Many species of vulture are under threat from man-made inventions; this has led to wounded and sick vultures presenting for veterinary treatment and in need of pain management. Following the devastating effect of diclofenac on vultures in South Asia, meloxicam was found to be very safe for vultures, as a treatment as well as through ingestion of meat from treated animals. Many studies investigated the safety of meloxicam, and all found it to be safe up to 2 mg/kg, which was deemed the maximum likely exposure through treated carcasses. All studies exposed the birds either through oral dosing, treated meat or intramuscular administration, no instances of toxicity where recorded and all birds remained healthy. In this case the bird was exposed to a single dose of 2 mg/kg, intravenously, with no signs of toxicity. This appears to be the first recorded instance of accidental intravenous administration of meloxicam in a vulture.
期刊介绍:
The Journal of the South African Veterinary Association is a contemporary multi-disciplinary scientific mouthpiece for Veterinary Science in South Africa and abroad. It provides veterinarians in South Africa and elsewhere in the world with current scientific information across the full spectrum of veterinary science. Its content therefore includes reviews on various topics, clinical and non-clinical articles, research articles and short communications as well as case reports and letters.