Accidental intravenous overdose of meloxicam in a Cape Vulture (Gyps coprotheres).

IF 0.5 4区 农林科学 Q3 VETERINARY SCIENCES
B A T Gazendam, K N Koeppel
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引用次数: 0

Abstract

Many species of vulture are under threat from man-made inventions; this has led to wounded and sick vultures presenting for veterinary treatment and in need of pain management. Following the devastating effect of diclofenac on vultures in South Asia, meloxicam was found to be very safe for vultures, as a treatment as well as through ingestion of meat from treated animals. Many studies investigated the safety of meloxicam, and all found it to be safe up to 2 mg/kg, which was deemed the maximum likely exposure through treated carcasses. All studies exposed the birds either through oral dosing, treated meat or intramuscular administration, no instances of toxicity where recorded and all birds remained healthy. In this case the bird was exposed to a single dose of 2 mg/kg, intravenously, with no signs of toxicity. This appears to be the first recorded instance of accidental intravenous administration of meloxicam in a vulture.

秃鹫意外静脉注射过量美洛昔康。
许多种类的秃鹫正受到人为发明的威胁;这导致受伤和生病的秃鹫需要兽医治疗,需要疼痛管理。继双氯芬酸对南亚秃鹫的毁灭性影响之后,人们发现美洛昔康对秃鹫来说是非常安全的,无论是作为一种治疗药物,还是通过摄入治疗过的动物的肉。许多研究调查了美洛昔康的安全性,所有研究都发现它在每公斤2毫克以下是安全的,这被认为是通过处理过的尸体接触的最大可能剂量。所有的研究都是通过口服给药、处理过的肉或肌肉注射给药,没有记录毒性事件,所有的鸟类都保持健康。在这种情况下,禽类静脉注射单剂量2mg /kg,没有毒性迹象。这似乎是第一个记录的例子,意外静脉注射美洛昔康在秃鹫。
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来源期刊
CiteScore
1.50
自引率
0.00%
发文量
23
审稿时长
22 weeks
期刊介绍: The Journal of the South African Veterinary Association is a contemporary multi-disciplinary scientific mouthpiece for Veterinary Science in South Africa and abroad. It provides veterinarians in South Africa and elsewhere in the world with current scientific information across the full spectrum of veterinary science. Its content therefore includes reviews on various topics, clinical and non-clinical articles, research articles and short communications as well as case reports and letters.
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