A Comprehensive Review of Behcet’s Disease Damage Assessment Tools

IF 4.7 3区医学 Q1 MEDICINE, RESEARCH & EXPERIMENTAL

Archives of Medical Research Pub Date : 2025-05-20 DOI:10.1016/j.arcmed.2025.103238

Alireza Khabbazi , Ehsan Mehrtabar , Saba Mehrtabar , Amirreza Khalaji , Aida Malek Mahdavi

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Abstract

Outcome assessment of rheumatic diseases has a significant role in evaluating the effect of various therapies in clinical studies and in the treatment of these patients in daily practice. Outcome assessment in rheumatic disorders is based on the evaluation of disease activity, quality of life, disability, and mortality caused by the disease. Behçet’s disease (BD) is a multisystem inflammatory condition that can cause damage to multiple organs. Damage assessment, along with assessment of BD activity, are two necessary and complementary components of BD outcome measures, based on Outcome Measures in Rheumatology. In clinical trials of BD, outcome assessment has been based on disease activity measures, which do not measure damage severity. In this review, we considered three damage indices that have recently been introduced to assess BD-related injury, including vasculitis damage index (VDI), Behçet’s syndrome overall damage index (BODI), and Behçet’s disease damage index (BDI).

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白塞病损害评估工具综述

风湿性疾病的结局评估在临床研究和日常治疗中对各种治疗方法的疗效评价中具有重要作用。风湿性疾病的结局评估是基于疾病活动性、生活质量、残疾和由疾病引起的死亡率的评估。behet病（BD）是一种多系统炎症性疾病，可引起多器官损伤。损害评估和BD活动评估是基于《风湿病学结果测量》的BD结果测量的两个必要和互补的组成部分。在双相障碍的临床试验中，结果评估是基于疾病活动度测量，而不是测量损害的严重程度。在这篇综述中，我们考虑了最近引入的用于评估bd相关损伤的三种损伤指标，包括血管炎损伤指数（VDI）、behet综合征整体损伤指数（BODI）和behet病损伤指数（BDI）。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Archives of Medical Research 医学-医学：研究与实验

CiteScore

12.50

自引率

0.00%

发文量

审稿时长

28 days

期刊介绍： Archives of Medical Research serves as a platform for publishing original peer-reviewed medical research, aiming to bridge gaps created by medical specialization. The journal covers three main categories - biomedical, clinical, and epidemiological contributions, along with review articles and preliminary communications. With an international scope, it presents the study of diseases from diverse perspectives, offering the medical community original investigations ranging from molecular biology to clinical epidemiology in a single publication.