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Correction to Validation of a Good Manufacturing Practice Procedure for the Production of [11C]AZD4747, a CNS Penetrant KRASG12c Inhibitor

IF 0.9 4区 医学 Q4 BIOCHEMICAL RESEARCH METHODS
Journal of labelled compounds & radiopharmaceuticals Pub Date : 2025-05-21 DOI:10.1002/jlcr.4149
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引用次数: 0

Abstract

J Labelled Comp Radiopharm. 2024 May 30;67(6):245-249.

The scheme depicting the labelling of [11C]AZD4747 shows the incorrect structure for both the precursor and the product. The position of the nitrogen atom and the stereochemistry of the seven-membered ring have been corrected.

The corrected reaction scheme is depicted below.

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