Endometrioid adenofibroma of ovary - a literature review.

Abstract

Background/objectives: Ovarian neoplasms are the third most common gynecological cancer and carry a poorer prognosis than breast cancer. Endometrioid borderline ovarian tumors (EBOTs) are intermediate epithelial lesions, histologically showing glandular patterns with mild to moderate atypia and no stromal invasion. Study selection for review: A comprehensive electronic search was conducted on PubMed to identify risk factors and etiological determinants associated with ovarian endometrioid adenofibroma (EA).

Case presentation: A 27-year-old woman with a left ovarian cyst underwent a laparoscopic procedure to remove the adnexa after imaging showed a 6 cm mass. Surgery was successful, and she was discharged without complications.

Conclusions: This study highlights the diagnostic challenges of EBOTs, the essential role of immunohistochemistry, and the need for careful surgical and fertility-preserving strategies. It also draws attention to possible risks linked to fertility treatments. Fertility preservation is crucial in young patients, favoring uterine and ovarian conservation. In early-stage, small, non-invasive tumors, laparoscopy is the preferred approach. EAs are uncommon benign ovarian tumors, accounting for approximately 1% of epithelial neoplasms, and are predominantly unilateral.