Fire needle pretreatment combined with ALA-PDT for Penile Bowen's disease: A case report

IF 3.1 3区医学 Q2 ONCOLOGY

Photodiagnosis and Photodynamic Therapy Pub Date : 2025-05-14 DOI:10.1016/j.pdpdt.2025.104631

Tianming Ma , Xiaoqing Xiang , Yanliang Li , Runqun Liu , Yunyun Cao

引用次数: 0

Abstract

Bowen's disease (BD), squamous cell carcinoma (SCC) in situ, presents treatment challenges when located on the penis. Primarily concerning potential scarring and functional impairment following standard surgical excision (e.g., Mohs micrographic surgery). Aminolevulinic acid photodynamic therapy (ALA-PDT) may provide a valuable alternative, especially for this sensitive anatomical site. This report describes the successful treatment of a case of penile BD using fire needle pretreatment immediately preceding ALA-PDT. The patient achieved complete clinical and histological remission and remained disease-free at 2 years of follow-up.

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火针预处理联合ALA-PDT治疗阴茎博文病1例。

鲍恩氏病（BD）是一种原位鳞状细胞癌（SCC），当其位于阴茎上时，其治疗面临挑战，主要涉及标准手术切除（例如莫氏显微摄影手术）后潜在的疤痕和功能损害。氨基乙酰丙酸光动力疗法（ALA-PDT）提供了一种有价值的替代方法，特别是对于这种敏感的解剖部位。本报告描述了在ALA-PDT之前立即使用火针预处理成功治疗阴茎BD的病例。患者达到完全的临床和组织学缓解，并在2年的随访中保持无病状态。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Photodiagnosis and Photodynamic Therapy ONCOLOGY-

CiteScore

5.80

自引率

24.20%

发文量

509

审稿时长

50 days

期刊介绍： Photodiagnosis and Photodynamic Therapy is an international journal for the dissemination of scientific knowledge and clinical developments of Photodiagnosis and Photodynamic Therapy in all medical specialties. The journal publishes original articles, review articles, case presentations, "how-to-do-it" articles, Letters to the Editor, short communications and relevant images with short descriptions. All submitted material is subject to a strict peer-review process.