{"title":"Engineered proxies and the illusion of de-extinction.","authors":"Dusko Ilic","doi":"10.1016/j.stemcr.2025.102505","DOIUrl":null,"url":null,"abstract":"<p><p>The recent creation of dire wolf-like canids by Colossal Biosciences marks a technical achievement in genome editing and synthetic embryology. But the project also demands a reevaluation of what we mean by \"de-extinction\"-and whether a phenotypic approximation constitutes species restoration.</p>","PeriodicalId":21885,"journal":{"name":"Stem Cell Reports","volume":" ","pages":"102505"},"PeriodicalIF":5.9000,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12181955/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Stem Cell Reports","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.stemcr.2025.102505","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/5/15 0:00:00","PubModel":"Epub","JCR":"Q1","JCRName":"CELL & TISSUE ENGINEERING","Score":null,"Total":0}
引用次数: 0
Abstract
The recent creation of dire wolf-like canids by Colossal Biosciences marks a technical achievement in genome editing and synthetic embryology. But the project also demands a reevaluation of what we mean by "de-extinction"-and whether a phenotypic approximation constitutes species restoration.
期刊介绍:
Stem Cell Reports publishes high-quality, peer-reviewed research presenting conceptual or practical advances across the breadth of stem cell research and its applications to medicine. Our particular focus on shorter, single-point articles, timely publication, strong editorial decision-making and scientific input by leaders in the field and a "scoop protection" mechanism are reasons to submit your best papers.