{"title":"Emerging strategies to develop novel genetically encoded biosensors.","authors":"Lili Chang, Jin Wang, Meng Wang, Yue Zhang","doi":"10.1016/j.tibtech.2025.04.014","DOIUrl":null,"url":null,"abstract":"<p><p>The current biosensor inventory is inadequate for the multitude of metabolites and proteins needing detection. Assisted by new technologies and research paradigms such as multi-omics analysis and de novo protein design, emerging strategies provide a promising avenue for the development of novel, tailored genetically encoded biosensors for various applications.</p>","PeriodicalId":23324,"journal":{"name":"Trends in biotechnology","volume":" ","pages":""},"PeriodicalIF":14.3000,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Trends in biotechnology","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.1016/j.tibtech.2025.04.014","RegionNum":1,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOTECHNOLOGY & APPLIED MICROBIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
The current biosensor inventory is inadequate for the multitude of metabolites and proteins needing detection. Assisted by new technologies and research paradigms such as multi-omics analysis and de novo protein design, emerging strategies provide a promising avenue for the development of novel, tailored genetically encoded biosensors for various applications.
期刊介绍:
Trends in Biotechnology publishes reviews and perspectives on the applied biological sciences, focusing on useful science applied to, derived from, or inspired by living systems.
The major themes that TIBTECH is interested in include:
Bioprocessing (biochemical engineering, applied enzymology, industrial biotechnology, biofuels, metabolic engineering)
Omics (genome editing, single-cell technologies, bioinformatics, synthetic biology)
Materials and devices (bionanotechnology, biomaterials, diagnostics/imaging/detection, soft robotics, biosensors/bioelectronics)
Therapeutics (biofabrication, stem cells, tissue engineering and regenerative medicine, antibodies and other protein drugs, drug delivery)
Agroenvironment (environmental engineering, bioremediation, genetically modified crops, sustainable development).