{"title":"Neutrophil Extracellular Traps and neutrophilic asthma.","authors":"Jiayi Xiang, Muyan Cui","doi":"10.1016/j.rmed.2025.108150","DOIUrl":null,"url":null,"abstract":"<p><p>There are more than 260 million asthma patients worldwide. How to provide targeted long-term standardized treatment and management still confuses clinical workers and patients. Neutrophilic asthma is a special type of asthma which is difficult to diagnose clinically and often associated with severe asthma and glucocorticoid resistance. Neutrophil Extracellular Traps (NETs) play an important role in the pathogenesis of this type of asthma particularly in children. This article explores the mechanism of NETs production, their association with neutrophilic asthma, biomarkers, and possible treatment options. A more detailed discussion is also provided on the diagnosis and treatment of children with neutrophilic asthma. Educational Aims The readers will gain an improved understanding of.</p>","PeriodicalId":21057,"journal":{"name":"Respiratory medicine","volume":" ","pages":"108150"},"PeriodicalIF":3.5000,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Respiratory medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1016/j.rmed.2025.108150","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 0
Abstract
There are more than 260 million asthma patients worldwide. How to provide targeted long-term standardized treatment and management still confuses clinical workers and patients. Neutrophilic asthma is a special type of asthma which is difficult to diagnose clinically and often associated with severe asthma and glucocorticoid resistance. Neutrophil Extracellular Traps (NETs) play an important role in the pathogenesis of this type of asthma particularly in children. This article explores the mechanism of NETs production, their association with neutrophilic asthma, biomarkers, and possible treatment options. A more detailed discussion is also provided on the diagnosis and treatment of children with neutrophilic asthma. Educational Aims The readers will gain an improved understanding of.
期刊介绍：
Respiratory Medicine is an internationally-renowned journal devoted to the rapid publication of clinically-relevant respiratory medicine research. It combines cutting-edge original research with state-of-the-art reviews dealing with all aspects of respiratory diseases and therapeutic interventions. Topics include adult and paediatric medicine, epidemiology, immunology and cell biology, physiology, occupational disorders, and the role of allergens and pollutants.
Respiratory Medicine is increasingly the journal of choice for publication of phased trial work, commenting on effectiveness, dosage and methods of action.
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