Yang Fu, Yuanxin Ge, Shixiong Yi, Qifeng Peng, Heng Jiang, Jie Zhou
{"title":"A review: advances of curcumin co-delivery biomaterials-based system in anti-tumor therapy","authors":"Yang Fu, Yuanxin Ge, Shixiong Yi, Qifeng Peng, Heng Jiang, Jie Zhou","doi":"10.1007/s10853-025-10903-9","DOIUrl":null,"url":null,"abstract":"<div><p>Curcumin, a widely utilized natural plant extract, has been reported for its applications in various clinical treatment scenarios, including anti-inflammatory, antioxidant, anti-tumor, antimicrobial, and anti-aging effects. However, curcumin’s properties such as low solubility in water and susceptibility to oxidation, among others, have hindered its drug delivery process and efficiency. Therefore, curcumin needs to be co-delivered with other molecules to achieve better anti-tumor therapeutic effects, such as other anti-tumor drugs, photothermal agents, and metal compounds, to enhance its anti-tumor efficacy. In this review, the current status of curcumin as a naturally synthesized extract and the research progress of its combined application with other molecules are summarized, and the authors also present their own perspectives on the future application of curcumin.</p></div>","PeriodicalId":645,"journal":{"name":"Journal of Materials Science","volume":"60 18","pages":"7492 - 7506"},"PeriodicalIF":3.5000,"publicationDate":"2025-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Materials Science","FirstCategoryId":"88","ListUrlMain":"https://link.springer.com/article/10.1007/s10853-025-10903-9","RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
Curcumin, a widely utilized natural plant extract, has been reported for its applications in various clinical treatment scenarios, including anti-inflammatory, antioxidant, anti-tumor, antimicrobial, and anti-aging effects. However, curcumin’s properties such as low solubility in water and susceptibility to oxidation, among others, have hindered its drug delivery process and efficiency. Therefore, curcumin needs to be co-delivered with other molecules to achieve better anti-tumor therapeutic effects, such as other anti-tumor drugs, photothermal agents, and metal compounds, to enhance its anti-tumor efficacy. In this review, the current status of curcumin as a naturally synthesized extract and the research progress of its combined application with other molecules are summarized, and the authors also present their own perspectives on the future application of curcumin.
期刊介绍：
The Journal of Materials Science publishes reviews, full-length papers, and short Communications recording original research results on, or techniques for studying the relationship between structure, properties, and uses of materials. The subjects are seen from international and interdisciplinary perspectives covering areas including metals, ceramics, glasses, polymers, electrical materials, composite materials, fibers, nanostructured materials, nanocomposites, and biological and biomedical materials. The Journal of Materials Science is now firmly established as the leading source of primary communication for scientists investigating the structure and properties of all engineering materials.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
