Comparison of rapid recovery outcomes between vNOTES hysterectomy and laparoscopic hysterectomy: a prospective study.

IF 1.6 3区 医学 Q2 SURGERY
Ying Tang, Chun-Ling Fang, Jun-Rong Huang, Xiao-Mei Chen, Xin Cai, Jia Wu, Hui-Quan Hu, Jun Li, Yue-Xi Luo
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引用次数: 0

Abstract

Background: This study was aimed at evaluating the postoperative outcomes of vaginal natural orifice transluminal endoscopic hysterectomy (vNOTEH).

Methods: This prospective cohort study was conducted for comparing recovery outcomes, the time to first anal exhaust and return-to-work (RTW) time in vNOTEH versus laparoscopic hysterectomy (LH) groups. Linear regression analysis and cox proportional hazards regression were employed for analyzing the association between the recovery outcomes and surgical procedures.

Results: Altogether 330 patients were enrolled, with 92 in vNOTEH group whereas 238 in LH group according to the surgical procedure. Among them, 22 patients undergoing vNOTEH and 76 patients receiving LH returned to work. The operation time, the first anal exhaust time, RTW time, postoperative hospitalization of vNOTEH group remarkably decreased relative to LH group (P<0.05). Linear regression analysis indicated that the vNOTES approach was related to the time to first anal exhaust. Besides, Kaplan-Meier curve demonstrated the shorter median time to first anal exhaust in vNOTEH group than that in LH group (48.0 h vs. 69.0 h, P < 0.001). For patients who returned to work, multivariate Cox logistic regression revealed that surgical approach and postoperative hospitalization were significantly related to the RTW time. Furthermore, Kaplan-Meier curve showed that the median RTW time significantly decreased in vNOTEH subgroup relative to that in LH subgroup (2.0 months vs.3.0 months, P = 0.011).

Conclusions and relevance: vNOTES in women might be advantageous in the earlier recovery of intestinal function and the earlier return to work after hysterectomy compared with laparoscopy.

Trial registration: This study has been registered at https://www.chictr.org.cn with registration NO. ChiCTR2200063125 on Sep 27, 2022. The minimal postoperative follow up period was 1 month.

vNOTES子宫切除术与腹腔镜子宫切除术快速恢复效果的比较:一项前瞻性研究。
背景:本研究旨在评价阴道自然孔腔内窥镜子宫切除术(vNOTEH)的术后效果。方法:本前瞻性队列研究比较了vNOTEH组和腹腔镜子宫切除术组的恢复结果、首次肛门排气时间和重返工作时间(RTW)。采用线性回归分析和cox比例风险回归分析恢复结果与手术方式的关系。结果:共纳入330例患者,根据手术方式,vNOTEH组92例,LH组238例。其中22例接受vNOTEH治疗,76例接受LH治疗的患者恢复工作。与LH组相比,vNOTES组的手术时间、第一次肛门排气时间、RTW时间、术后住院时间均显著减少(p)。结论及相关性:与腹腔镜相比,vNOTES组在女性子宫切除术后肠功能恢复较早,重返工作岗位较早。试验注册:本研究已在https://www.chictr.org.cn注册,注册号为:ChiCTR2200063125,于2022年9月27日。术后最短随访时间为1个月。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
BMC Surgery
BMC Surgery SURGERY-
CiteScore
2.90
自引率
5.30%
发文量
391
审稿时长
58 days
期刊介绍: BMC Surgery is an open access, peer-reviewed journal that considers articles on surgical research, training, and practice.
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