[Association between insulin resistance and uterine volume in girls with idiopathic central precocious puberty].

Q3 Medicine

中国当代儿科杂志 Pub Date : 2025-04-15 DOI:10.7499/j.issn.1008-8830.2411003

Hong-Ru Zhang, Ya Xiao, Shu-Qin Jiang, Jun Sun, Wen-Hui Shi, Jin-Bo Li, Ying Yang, Wei Wang

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引用次数: 0

Abstract

Objectives: To investigate the association between insulin resistance and uterine volume in girls with idiopathic central precocious puberty (ICPP).

Methods: A retrospective study was conducted involving 61 girls diagnosed with ICPP who visited the pediatric growth and development clinic of the Third Affiliated Hospital of Zhengzhou University between January 2022 and September 2024, designated as the ICPP group, and 61 normally developing girls as the control group. The differences in insulin resistance index (homeostasis model assessment of insulin resistance, HOMA-IR), uterine volume, and other indicators between the two groups were compared, and the relationship between insulin resistance and uterine volume in these girls was analyzed.

Results: The uterine volume and HOMA-IR level in the ICPP group were significantly higher than those in the control group (P<0.05). Correlation analysis revealed that there was a positive correlation between HOMA-IR level and uterine volume in the ICPP group (r_s=0.643, P<0.001). Multiple linear regression analysis indicated that as HOMA-IR increased,uterine volume in the girls tended to increase (P<0.05).

Conclusions: There is an association between insulin resistance and uterine volume in girls with ICPP, and as HOMA-IR increases, uterine volume in the girls also increases.

查看原文本刊更多论文

[特发性中枢性性早熟女孩胰岛素抵抗与子宫体积的关系]。

目的：探讨特发性中枢性性早熟（ICPP）女童胰岛素抵抗与子宫体积的关系。方法：选取2022年1月至2024年9月在郑州大学第三附属医院儿童生长发育门诊就诊的61例确诊为ICPP的女童作为ICPP组，61例发育正常的女童作为对照组。比较两组女童胰岛素抵抗指数（胰岛素抵抗稳态模型评估，HOMA-IR）、子宫体积等指标的差异，分析胰岛素抵抗与子宫体积的关系。结果：ICPP组子宫体积和HOMA-IR水平均显著高于对照组（pr =0.643, ppp）。结论：ICPP女孩的胰岛素抵抗与子宫体积存在相关性，且随着HOMA-IR的升高，子宫体积也随之增大。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

中国当代儿科杂志 Medicine-Pediatrics, Perinatology and Child Health

CiteScore

1.50

自引率

0.00%

发文量

5006

期刊介绍： The Chinese Journal of Contemporary Pediatrics (CJCP) is a peer-reviewed open access periodical in the field of pediatrics that is sponsored by the Central South University/Xiangya Hospital of Central South University and under the auspices of the Ministry of Education of China. It is cited as a source in the scientific and technological papers of Chinese journals, the Chinese Science Citation Database (CSCD), and is one of the core Chinese periodicals in the Peking University Library. CJCP has been indexed by MEDLINE/PubMed/PMC of the American National Library, American Chemical Abstracts (CA), Holland Medical Abstracts (EM), Western Pacific Region Index Medicus (WPRIM), Scopus and EBSCO. It is a monthly periodical published on the 15th of every month, and is distributed both at home and overseas. The Chinese series publication number is CN 43-1301/R；ISSN 1008-8830. The tenet of CJCP is to “reflect the latest advances and be open to the world”. The periodical reports the most recent advances in the contemporary pediatric field. The majority of the readership is pediatric doctors and researchers.