Not every nasal block is allergic rhinitis: a case report of sinonasal malignant melanoma.

IF 0.4 Q4 SURGERY
Journal of Surgical Case Reports Pub Date : 2025-05-13 eCollection Date: 2025-05-01 DOI:10.1093/jscr/rjaf295
Rula Naqi, Vineeth Haridas, Ismail Kandiyil, Mohammed Al-Shehabi, Mai Nasser, Amal Al-Abdullah
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引用次数: 0

Abstract

Sinonasal malignant melanoma (SNMM) is an extremely rare and aggressive sinonasal tumor. It has nonspecific risk factors and clinical presentation which require a high index of suspicion. In this case report we present a case of a 47-year-old male who initially had persistent nasal obstruction not responding to intranasal steroids. Comprehensive imaging and histopathological studies confirmed SNMM. He underwent incomplete maxillectomy resection followed by immunotherapy abroad. Within 6 months period he had recurrence of the disease. As this disease is a rare entity, there are no specific treatment guidelines, however, surgical intervention is agreed to be the mainstay of treatment. Although their effectiveness is still controversial, radiation therapy, chemotherapy, immunological and biological therapies are adjuvant options. Multidisciplinary team approach is necessary to provide the optimal treatment plan, along with close follow up. Continuous research and clinical trials are still needed to ensure appropriate diagnosis and management of this rare entity.

并非所有鼻阻塞都是过敏性鼻炎:鼻窦恶性黑色素瘤1例报告。
鼻窦恶性黑色素瘤(SNMM)是一种极其罕见的侵袭性鼻窦肿瘤。它具有非特异性的危险因素和临床表现,需要高度怀疑。在这个病例报告中,我们提出了一个47岁的男性病例,他最初患有持续性鼻塞,鼻内类固醇治疗无效。综合影像学和组织病理学检查证实为SNMM。他在国外接受了不完全上颌切除和免疫治疗。6个月内他的病复发了。由于这种疾病是一种罕见的实体,没有具体的治疗指南,然而,手术干预被认为是主要的治疗方法。虽然它们的有效性仍有争议,但放射治疗、化疗、免疫和生物治疗是辅助治疗的选择。多学科团队的方法是必要的,以提供最佳的治疗方案,以及密切的随访。仍然需要持续的研究和临床试验,以确保适当的诊断和管理这种罕见的实体。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
0.70
自引率
0.00%
发文量
559
审稿时长
11 weeks
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