Nandrolone (17-Nortestosterone) And Glucose Metabolism: From Ugly Duckling To Handsome Swan.

IF 0.8 4区医学 Q3 MEDICINE, GENERAL & INTERNAL

Journal of the Pakistan Medical Association Pub Date : 2025-04-01 DOI:10.47391/JPMA.25-27

Sanjay Kalra, Atul Dhingra, Nitin Kapoor

引用次数: 0

Abstract

Glucosarcopenia, or sarcopenia coexisting with diabetes, is a common condition. Caused by various factors, including poor glucose control, as well as some glucoselowering therapies, sarcopenia negatively impacts quality of life and long-term health. Nandrolone, or 19- nortestosterone, is a selective anabolic receptor modulator (SARM), classified as an anabolic-androgenic steroid (AAS). A review of its pharmacological properties suggests that it may be used as therapy for sarcopenia, along with medical nutrition therapy and resistance exercise training. This review suggests a practical and pragmatic approach towards ensuring safe and smart usage of nandrolone in glucosarcopenia management.

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诺龙（17-去睾酮）和葡萄糖代谢：从丑小鸭到英俊天鹅。

糖少症或与糖尿病共存的肌肉减少症是一种常见的疾病。肌肉减少症由多种因素引起，包括血糖控制不良，以及一些降糖疗法，对生活质量和长期健康产生负面影响。诺龙，或称去甲睾酮，是一种选择性合成代谢受体调节剂（SARM），被归类为合成代谢雄激素类固醇（AAS）。对其药理特性的回顾表明，它可以作为治疗肌肉减少症，连同医学营养疗法和阻力运动训练。本综述提出了一种切实可行的方法，以确保在血糖减少症治疗中安全、明智地使用诺龙。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of the Pakistan Medical Association Medicine-General Medicine

CiteScore

1.10

自引率

11.10%

发文量

983

审稿时长

3-6 weeks

期刊介绍： Primarily being a medical journal, JPMA publishes scholarly research focusing on the various fields in the areas of health and medical education. It publishes original research describing recent advances in health particularly clinical studies, clinical trials, assessments of pathogens of diagnostic importance, medical genetics and epidemiological studies. Review articles highlighting importance of various issues in the domain of public health, drug research and medical education are also accepted. As a leading journal of South Asia, JPMA remains cognizant of the recent advances in the rapidly growing fields of biomedical sciences, it invites and encourages scholars to write short reviews and invited editorials on the emerging issues. We particularly aim to promote health standards of developing countries by encouraging manuscript submissions on issues affecting the public health and health delivery services.