A metabolon at the heart of steroidal biosynthesis.

IF 17.3 1区生物学 Q1 PLANT SCIENCES

Trends in Plant Science Pub Date : 2025-04-09 DOI:10.1016/j.tplants.2025.03.015

Tsubasa Shoji, Satoru Sawai

引用次数: 0

Abstract

Metabolons, dynamic enzyme assemblies critical for substrate channeling, underpin specialized metabolism. Recent studies by Boccia et al. and Jozwiak et al. in Solanum uncovered a cellulose synthase-like protein that orchestrates metabolon formation, functioning dually as a scaffold and glucuronosyltransferase in steroidal glycoalkaloid (SGA) and steroidal saponin (SS) biosynthesis, offering profound opportunities for metabolic engineering.

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类固醇生物合成的核心代谢物。

代谢，对底物通道至关重要的动态酶组合，支持专门的代谢。Boccia等人和Jozwiak等人最近在茄属植物上的研究发现了一种纤维素合成酶样蛋白，它可以协调代谢的形成，在甾体糖生物碱（SGA）和甾体皂苷（SS）的生物合成中起支架和葡萄糖醛基转移酶的双重作用，为代谢工程提供了深刻的机会。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Trends in Plant Science 生物-植物科学

CiteScore

31.30

自引率

2.00%

发文量

196

审稿时长

6-12 weeks

期刊介绍： Trends in Plant Science is the primary monthly review journal in plant science, encompassing a wide range from molecular biology to ecology. It offers concise and accessible reviews and opinions on fundamental plant science topics, providing quick insights into current thinking and developments in plant biology. Geared towards researchers, students, and teachers, the articles are authoritative, authored by both established leaders in the field and emerging talents.