Hepatic Arterial Infusion Chemotherapy for Hepatocellular Carcinoma: A Three-Dimensional Visualization Perspective.

IF 4.2 3区 医学 Q2 ONCOLOGY
Journal of Hepatocellular Carcinoma Pub Date : 2025-04-28 eCollection Date: 2025-01-01 DOI:10.2147/JHC.S513695
Yong Tan, Ping-Ping Li, Hui Liu, Jian-Yong Zhu, Qing-Song Wu
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引用次数: 0

Abstract

In Asia, hepatic arterial infusion chemotherapy is an alternative therapeutic option for hepatocellular carcinoma (HCC). However, the current application of HAIC lacks precision, as drug dosages are typically calculated based solely on body surface area. This approach often results in underdosing for patients with larger liver tumors or greater liver volume and overdosing for those with smaller liver tumors or reduced liver volume. Consequently, determining drug dosages according to the specific target volume requiring treatment may enhance individualized and standardized therapy for HCC, aligning with the principles of precision oncology.

肝动脉输注化疗治疗肝细胞癌:三维可视化视角。
在亚洲,肝动脉灌注化疗是肝细胞癌(HCC)的另一种治疗选择。然而,目前HAIC的应用缺乏精度,因为药物剂量通常仅根据体表面积计算。这种方法通常导致肝肿瘤较大或肝体积较大的患者给药不足,而肝肿瘤较小或肝体积减小的患者给药过量。因此,根据需要治疗的特定靶体积确定药物剂量,可以加强HCC的个体化和标准化治疗,符合精准肿瘤学的原则。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
0.50
自引率
2.40%
发文量
108
审稿时长
16 weeks
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