Response to: Evaluating time-lapse imaging systems for embryo incubation and selection in ART: a critical review of a randomized controlled trial.

IF 3.7 2区医学 Q1 OBSTETRICS & GYNECOLOGY

Reproductive biomedicine online Pub Date : 2025-03-18 DOI:10.1016/j.rbmo.2025.104938

Priya Bhide, David Yl Chan, M Carmen Pardo, Teresa Perez, Khalid S Khan, Shakila Thangaratinam

引用次数: 0

Abstract

The concerns raised by the authors of this commentary are largely addressed in the paper and the requested information is available in the supplementary materials and the published trial protocol referenced in the paper. We have further detailed some information to address their concerns. The planned effect size was based on the results reported by the largest randomized controlled trial at the start of our trial and supported by peer review and patient and clinician input. The trial was powered for the primary outcome of live birth, which we have reported. All reported secondary outcomes and subgroup analyses are only hypothesis generating.

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评价延时成像系统在抗逆转录病毒治疗中的胚胎孵化和选择：一项随机对照试验的重要回顾。

这篇评论的作者所提出的问题在论文中大部分得到了解决，所要求的信息可在补充材料和论文中引用的已发表的试验方案中获得。我们已经进一步详细介绍了一些情况，以解决他们的关切。计划的效应量是基于我们试验开始时最大的随机对照试验报告的结果，并得到同行评审、患者和临床医生输入的支持。该试验的主要结果是活产，我们已经报道了这一点。所有报告的次要结果和亚组分析都只是假设。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Reproductive biomedicine online 医学-妇产科学

CiteScore

7.20

自引率

7.50%

发文量

391

审稿时长

50 days

期刊介绍： Reproductive BioMedicine Online covers the formation, growth and differentiation of the human embryo. It is intended to bring to public attention new research on biological and clinical research on human reproduction and the human embryo including relevant studies on animals. It is published by a group of scientists and clinicians working in these fields of study. Its audience comprises researchers, clinicians, practitioners, academics and patients. Context: The period of human embryonic growth covered is between the formation of the primordial germ cells in the fetus until mid-pregnancy. High quality research on lower animals is included if it helps to clarify the human situation. Studies progressing to birth and later are published if they have a direct bearing on events in the earlier stages of pregnancy.