Florence Birru, Anne Hicks, Jake Mandziuk, Ioana Bratu
{"title":"Pneumatoceles or Not? Case Reports on Pulmonary Cystic Lesions in Infants.","authors":"Florence Birru, Anne Hicks, Jake Mandziuk, Ioana Bratu","doi":"10.1177/10935266251338562","DOIUrl":null,"url":null,"abstract":"<p><p>Pulmonary cystic lesions in infants are uncommon and can present diagnostic challenges due to overlapping radiologic features with other cystic lung conditions. We present 2 cases of left lung cystic lesions in infants. Initial high-resolution computed tomography (HRCT) suggested differential diagnoses, including pneumatocele, type I congenital pulmonary airway malformation (CPAM), or a solitary cystic lymphangioma. Definitive diagnosis was achieved through histopathological examination after left lower lobectomy and resection of the lesion. These cases highlight the challenges in accurately diagnosing pulmonary cystic lesions, given the limitations of imaging alone.</p>","PeriodicalId":54634,"journal":{"name":"Pediatric and Developmental Pathology","volume":" ","pages":"400-405"},"PeriodicalIF":1.3000,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12426324/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pediatric and Developmental Pathology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1177/10935266251338562","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/5/12 0:00:00","PubModel":"Epub","JCR":"Q3","JCRName":"PATHOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Pulmonary cystic lesions in infants are uncommon and can present diagnostic challenges due to overlapping radiologic features with other cystic lung conditions. We present 2 cases of left lung cystic lesions in infants. Initial high-resolution computed tomography (HRCT) suggested differential diagnoses, including pneumatocele, type I congenital pulmonary airway malformation (CPAM), or a solitary cystic lymphangioma. Definitive diagnosis was achieved through histopathological examination after left lower lobectomy and resection of the lesion. These cases highlight the challenges in accurately diagnosing pulmonary cystic lesions, given the limitations of imaging alone.
期刊介绍:
The Journal covers the spectrum of disorders of early development (including embryology, placentology, and teratology), gestational and perinatal diseases, and all diseases of childhood. Studies may be in any field of experimental, anatomic, or clinical pathology, including molecular pathology. Case reports are published only if they provide new insights into disease mechanisms or new information.