Novel Insights to Mitochondrial Impact in Aging Skeletal Muscle.

IF 4.9 2区医学 Q1 PHYSIOLOGY

Exercise and Sport Sciences Reviews Pub Date : 2025-05-01 DOI:10.1249/JES.0000000000000364

Maya Semel, Cole Lukasiewicz, Russell T Hepple

引用次数: 0

Abstract

Abstract: Our Perspective for Progress highlights sex differences in skeletal muscle mitochondrial function that evolve with aging, with an influence of denervation emerging in advanced age. Gaps include knowledge about mitochondrial alterations in microdomains of muscle fibers, plasticity of the mitochondrial reticulum to acute muscle contractions, and advanced age of both sexes.

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线粒体对老化骨骼肌影响的新见解。

摘要：我们的进展观点强调了骨骼肌线粒体功能的性别差异，这些功能随着年龄的增长而进化，并在老年时出现神经支配的影响。空白包括肌纤维微域线粒体改变的知识，线粒体网对急性肌肉收缩的可塑性，以及男女年龄的增长。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Exercise and Sport Sciences Reviews 社会科学-生理学

CiteScore

10.70

自引率

1.80%

发文量

期刊介绍： Exercise and Sport Sciences Reviews made the transition from an annual hardcover series book to a quarterly journal in January 2000. The mission of this American College of Sports Medicine publication is to provide premier quarterly reviews of the most contemporary scientific, medical, and research-based topics emerging in the field of sports medicine and exercise science. The publication strives to provide the most relevant, topical information to students, professors, clinicians, scientists, and professionals for practical and research applications.