Elwira Bakula-Zalewska, Henryk A. Domanski, Jerzy Klijanienko
{"title":"Fine-Needle Aspiration of Parotid Gland Sialoblastoma. Two New Cases and Literature Review","authors":"Elwira Bakula-Zalewska, Henryk A. Domanski, Jerzy Klijanienko","doi":"10.1002/dc.25480","DOIUrl":null,"url":null,"abstract":"<div>\n \n <p>Sialoblastoma is an exceedingly rare, low-grade malignancy, most frequently arising in the parotid gland. Only four case reports detailing the cytomorphology of this neoplasm exist in the English literature. Here, we describe the cytological features, histopathology, and clinical data of sialoblastomas presented at birth in two additional patients. Both neoplasms were initially examined by fine-needle aspiration (FNA) followed by surgical excision of the tumors. Smears showed hypercellularity and basaloid round to oval cells isolated or arranged in three-dimensional clusters. Papillary and acinar configurations, metachromatic pink stromal fragments, and hyaline globules were also present. One case was diagnosed as a neoplasm of unclear malignant potential and the second as malignant.</p>\n </div>","PeriodicalId":11349,"journal":{"name":"Diagnostic Cytopathology","volume":"53 8","pages":"E155-E159"},"PeriodicalIF":1.0000,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Diagnostic Cytopathology","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/dc.25480","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"MEDICAL LABORATORY TECHNOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Sialoblastoma is an exceedingly rare, low-grade malignancy, most frequently arising in the parotid gland. Only four case reports detailing the cytomorphology of this neoplasm exist in the English literature. Here, we describe the cytological features, histopathology, and clinical data of sialoblastomas presented at birth in two additional patients. Both neoplasms were initially examined by fine-needle aspiration (FNA) followed by surgical excision of the tumors. Smears showed hypercellularity and basaloid round to oval cells isolated or arranged in three-dimensional clusters. Papillary and acinar configurations, metachromatic pink stromal fragments, and hyaline globules were also present. One case was diagnosed as a neoplasm of unclear malignant potential and the second as malignant.
期刊介绍：
Diagnostic Cytopathology is intended to provide a forum for the exchange of information in the field of cytopathology, with special emphasis on the practical, clinical aspects of the discipline. The editors invite original scientific articles, as well as special review articles, feature articles, and letters to the editor, from laboratory professionals engaged in the practice of cytopathology. Manuscripts are accepted for publication on the basis of scientific merit, practical significance, and suitability for publication in a journal dedicated to this discipline. Original articles can be considered only with the understanding that they have never been published before and that they have not been submitted for simultaneous review to another publication.
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