What is the Role of Primary Prevention of Obesity in an Age of Effective Pharmaceuticals?

IF 9.5 2区医学 Q1 ENDOCRINOLOGY & METABOLISM

Current Obesity Reports Pub Date : 2025-05-07 DOI:10.1007/s13679-025-00632-0

María Gómez-Martín, Oliver J Canfell, Li Kheng Chai, Anna K Jansson, Robyn Littlewood, Clair Sullivan, Dawn Power, Erin D Clarke, Louisa Ells, Nienke De Vlieger, Tracy L Burrows, Clare E Collins

{"title":"What is the Role of Primary Prevention of Obesity in an Age of Effective Pharmaceuticals?","authors":"María Gómez-Martín, Oliver J Canfell, Li Kheng Chai, Anna K Jansson, Robyn Littlewood, Clair Sullivan, Dawn Power, Erin D Clarke, Louisa Ells, Nienke De Vlieger, Tracy L Burrows, Clare E Collins","doi":"10.1007/s13679-025-00632-0","DOIUrl":null,"url":null,"abstract":"Purpose of review: To examine the evidence and continuing role of strategies for the primary prevention and treatment of obesity in the context of effective obesity pharmacotherapies, through a narrative review.Recent findings: Global policies to improve nutritional labelling and reduce sugar-sweetened beverages consumption have been implemented worldwide (> 45 countries) with some success which varies by population and environment. Tailored behavioural interventions are effective and essential to reduce individual risk of progression from preclinical to clinical obesity. Pharmacotherapies are powerful treatment agents for clinical obesity but must consider nutritional and metabolic risks of use and discontinuation. The obesogenic environment continues to undermine individual agency to adopt healthier dietary and physical activity patterns. Population health informatics tools could inform tailored interventions based on real-time risk and contribute to obesity prevention and treatment. Efforts to rebalance investment towards obesity prevention must continue to improve population health and reduce healthcare burden.","PeriodicalId":10846,"journal":{"name":"Current Obesity Reports","volume":"14 1","pages":"39"},"PeriodicalIF":9.5000,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12058953/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Obesity Reports","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s13679-025-00632-0","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ENDOCRINOLOGY & METABOLISM","Score":null,"Total":0}

引用次数: 0

Abstract

Purpose of review: To examine the evidence and continuing role of strategies for the primary prevention and treatment of obesity in the context of effective obesity pharmacotherapies, through a narrative review.

Recent findings: Global policies to improve nutritional labelling and reduce sugar-sweetened beverages consumption have been implemented worldwide (> 45 countries) with some success which varies by population and environment. Tailored behavioural interventions are effective and essential to reduce individual risk of progression from preclinical to clinical obesity. Pharmacotherapies are powerful treatment agents for clinical obesity but must consider nutritional and metabolic risks of use and discontinuation. The obesogenic environment continues to undermine individual agency to adopt healthier dietary and physical activity patterns. Population health informatics tools could inform tailored interventions based on real-time risk and contribute to obesity prevention and treatment. Efforts to rebalance investment towards obesity prevention must continue to improve population health and reduce healthcare burden.

查看原文本刊更多论文

在一个有效药物的时代，初级预防肥胖的作用是什么？

综述目的：通过一篇叙述性综述，探讨在有效的肥胖药物治疗背景下，肥胖症初级预防和治疗策略的证据和持续作用。最近的发现：改善营养标签和减少含糖饮料消费的全球政策已在世界范围内实施（bbbb45个国家），并取得了一些成功，但因人口和环境而异。量身定制的行为干预对于降低个体从临床前肥胖发展到临床肥胖的风险是有效和必要的。药物治疗是临床肥胖的有力治疗手段，但必须考虑使用和停药的营养和代谢风险。致肥环境继续破坏个体机构采取更健康的饮食和体育活动模式。人口健康信息学工具可以根据实时风险为量身定制的干预措施提供信息，并有助于预防和治疗肥胖。重新平衡投资以预防肥胖的努力必须继续改善人口健康并减轻医疗保健负担。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Current Obesity Reports Medicine-General Medicine

CiteScore

16.40

自引率

1.10%

发文量

期刊介绍： The main objective of Current Obesity Reports is to provide expert review articles on recent advancements in the interdisciplinary field of obesity research. Our aim is to offer clear, insightful, and balanced contributions that will benefit all individuals involved in the treatment and prevention of obesity, as well as related conditions such as cardiovascular diseases, endocrine disorders, gynecological issues, cancer, mental health, respiratory complications, and rheumatological diseases. We strive to redefine the way knowledge is expressed and provide organized content for the benefit of our readership.