Optimizing outcomes in heart transplantation: multidisciplinary Heart Teams and mechanical circulatory support for primary graft dysfunction.

IF 1.7 4区医学 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS

European Heart Journal Supplements Pub Date : 2025-04-28 eCollection Date: 2025-04-01 DOI:10.1093/eurheartjsupp/suaf003

Assad Haneya, Pia Lanmüller, Bernd Panholzer, Wiebke Sommer, Wiktor Kuliczkowski, Mateusz Sokolski, Roman Przybylski, Bastian Schmack, Sadeq Ali-Hasan-Al-Saegh, Sho Takemoto, Rachad Zayat, Nikos Werner

引用次数: 0

Abstract

Heart transplantation (HTx) is a definitive treatment for selected patients with advanced heart failure. However, primary graft dysfunction (PGD), a severe early complication, is a major cause of post-HTx morbidity and mortality. This paper explores the pathophysiology, diagnostic approaches, and management strategies for PGD, with a particular focus on temporary mechanical circulatory support (MCS) devices such as venoarterial extracorporeal membrane oxygenation and Impella. It also highlights the essential role of the multidisciplinary Heart Team in optimizing outcomes through patient-tailored MCS selection and timely intervention.

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优化心脏移植的结果：多学科心脏小组和机械循环支持原发性移植物功能障碍。

心脏移植（HTx）是晚期心力衰竭患者的最终治疗方法。然而，原发性移植物功能障碍（PGD）是一种严重的早期并发症，是htx术后发病率和死亡率的主要原因。本文探讨了PGD的病理生理学，诊断方法和管理策略，特别关注临时机械循环支持（MCS）设备，如静脉动脉体外膜氧合和Impella。它还强调了多学科心脏团队通过患者定制的MCS选择和及时干预来优化结果的重要作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

European Heart Journal Supplements 医学-心血管系统

CiteScore

3.00

自引率

0.00%

发文量

575

审稿时长

12 months

期刊介绍： The European Heart Journal Supplements (EHJs) is a long standing member of the ESC Journal Family that serves as a publication medium for supplemental issues of the flagship European Heart Journal. Traditionally EHJs published a broad range of articles from symposia to special issues on specific topics of interest. The Editor-in-Chief, Professor Roberto Ferrari, together with his team of eminent Associate Editors: Professor Francisco Fernández-Avilés, Professors Jeroen Bax, Michael Böhm, Frank Ruschitzka, and Thomas Lüscher from the European Heart Journal, has implemented a change of focus for the journal. This entirely refreshed version of the European Heart Journal Supplements now bears the subtitle the Heart of the Matter to give recognition to the focus the journal now has. The EHJs – the Heart of the Matter intends to offer a dedicated, scientific space for the ESC, Institutions, National and Affiliate Societies, Associations, Working Groups and Councils to disseminate their important successes globally.