Measuring early vascular aging in youth: an expert consensus document from the Youth Vascular Consortium.

IF 3.3 2区医学 Q1 PERIPHERAL VASCULAR DISEASE

Journal of Hypertension Pub Date : 2025-05-06 DOI:10.1097/HJH.0000000000004039

Jeanne Hersant, Ruan Kruger, Elisabetta Bianchini, Karsten Königstein, Manish D Sinha, Erzsébet V Hidvégi, Vimarsha Kodithuwakku, José Geraldo Mill, Alejandro Diaz, Yanina Zócalo, Daniel Bia, David Celermajer, Henner Hanssen, Madeleine Johansson, Giacomo Pucci, Mieczysław Litwin, Keeron Stone, Christopher J A Pugh, Lee Stoner, Elaine M Urbina, Rosa Maria Bruno, Peter M Nilsson, Rachel E Climie

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引用次数: 0

Abstract

Since the conceptualization of early vascular aging (EVA) in 2008, significant efforts have been made to develop and improve its assessment. Initially lead by the investigation of arterial stiffness through pulse wave velocity (PWV), several additional vascular aging biomarkers have gained prominence in recent years. Despite expanding literature addressing methodological concerns associated with these biomarkers in youth, a standardized approach for clinical evaluation of EVA remains elusive, leaving pertinent gaps in understanding the optimal methodology. This article, resulting from international consensus efforts from the Youth Vascular Consortium, aims to provide an updated overview of methods available to measure EVA in youth and to discuss challenges in translating these methods into clinical practice.

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测量早期血管老化在青年：专家共识文件从青年血管协会。

自2008年提出早期血管老化（EVA）的概念以来，人们对其评估进行了大量的研究和完善。最初是通过脉冲波速度（PWV）研究动脉硬度，近年来，一些额外的血管衰老生物标志物得到了重视。尽管越来越多的文献讨论了与青少年这些生物标志物相关的方法学问题，但EVA临床评估的标准化方法仍然难以捉摸，在理解最佳方法学方面留下了相关的空白。这篇文章来自青年血管协会的国际共识，旨在提供测量青年EVA的最新方法概述，并讨论将这些方法转化为临床实践所面临的挑战。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Hypertension 医学-外周血管病

CiteScore

7.90

自引率

6.10%

发文量

1389

审稿时长

3 months

期刊介绍： The Journal of Hypertension publishes papers reporting original clinical and experimental research which are of a high standard and which contribute to the advancement of knowledge in the field of hypertension. The Journal publishes full papers, reviews or editorials (normally by invitation), and correspondence.