Serum Markers of Abnormal Placental Attachment in Pregnant Women.

IF 0.9 4区医学 Q4 MEDICINE, RESEARCH & EXPERIMENTAL

Bulletin of Experimental Biology and Medicine Pub Date : 2025-03-01 Epub Date: 2025-04-28 DOI:10.1007/s10517-025-06397-9

K A Artemyeva, I A Kulikov, N V Nizyaeva, I I Stepanova, N B Tikhonova, L M Mikhaleva

引用次数: 0

Abstract

The changes in serum concentrations of glycodelin A, placental α1-microglobulin, and adiponectin in pregnant women were studied and the possibility of using them for predicting placenta accreta spectrum (PAS) was evaluated. Significantly reduced serum levels of all studied proteins and higher number cases of cesarean sections were found in women with PAS. A formula for predicting PAS was developed. It was found that patient's score ⩾ 8 indicates the presence of PAS with high sensitivity and specificity.

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孕妇胎盘附着异常的血清标志物。

研究妊娠妇女血清糖苷A、胎盘α - 1微球蛋白和脂联素浓度的变化，并评价其用于预测胎盘增生谱（PAS）的可能性。所有研究蛋白的血清水平均显著降低，在PAS患者中发现剖宫产的病例较多。提出了一个预测PAS的公式。发现患者评分大于或等于8表明PAS的存在具有高灵敏度和特异性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Bulletin of Experimental Biology and Medicine 医学-医学：研究与实验

CiteScore

1.50

自引率

14.30%

发文量

265

审稿时长

2 months

期刊介绍： Bulletin of Experimental Biology and Medicine presents original peer reviewed research papers and brief reports on priority new research results in physiology, biochemistry, biophysics, pharmacology, immunology, microbiology, genetics, oncology, etc. Novel trends in science are covered in new sections of the journal - Biogerontology and Human Ecology - that first appeared in 2005. World scientific interest in stem cells prompted inclusion into Bulletin of Experimental Biology and Medicine a quarterly scientific journal Cell Technologies in Biology and Medicine (a new Russian Academy of Medical Sciences publication since 2005). It publishes only original papers from the leading research institutions on molecular biology of stem and progenitor cells, stem cell as the basis of gene therapy, molecular language of cell-to-cell communication, cytokines, chemokines, growth and other factors, pilot projects on clinical use of stem and progenitor cells. The Russian Volume Year is published in English from April.