Primary Sjögren disease patients of Asian and Middle Eastern ancestry have early-onset but similar disease activity

Abstract

Sjögren disease (SjD) is a commonly encountered systemic autoimmune disease. We performed a single-centred study of 147 patients with primary SjD and found that SjD patients of Asian and Middle Eastern ancestry had earlier onset disease than Caucasian patients. It is likely that genetic factors dictate disease characteristics and future studies to dissect the biological basis for these differences are warranted.