Hyperammonaemia during allogeneic stem cell transplantation: distinct aetiology, importance of recognition and proposed treatment algorithm

IF 1.8 4区医学 Q2 MEDICINE, GENERAL & INTERNAL

Internal Medicine Journal Pub Date : 2025-04-15 DOI:10.1111/imj.70052

Jeremy D. Clark, James R. Anstey, David Ritchie, Timothy Fazio

引用次数: 0

Abstract

Hyperammonaemia during stem cell transplant is a distinct biochemical and clinical entity. It has a different pathological driver from other common forms of hyperammonaemia. Early recognition of this pathology and an understanding of its biochemical, pathological and microbiological aspects inform an aggressive management algorithm.

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同种异体干细胞移植期间的高氨血症：不同的病因，识别的重要性和提出的治疗算法

干细胞移植期间的高氨血症是一个独特的生化和临床实体。它与其他常见的高氨血症有不同的病理驱动因素。对这种病理的早期认识以及对其生化、病理和微生物学方面的理解为积极的管理算法提供了信息。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Internal Medicine Journal 医学-医学：内科

CiteScore

3.50

自引率

4.80%

发文量

600

审稿时长

3-6 weeks

期刊介绍： The Internal Medicine Journal is the official journal of the Adult Medicine Division of The Royal Australasian College of Physicians (RACP). Its purpose is to publish high-quality internationally competitive peer-reviewed original medical research, both laboratory and clinical, relating to the study and research of human disease. Papers will be considered from all areas of medical practice and science. The Journal also has a major role in continuing medical education and publishes review articles relevant to physician education.