Repeated CD107a Staining Enables Identification of Serial Degranulating NK Cells

IF 4.5 3区医学 Q2 IMMUNOLOGY

European Journal of Immunology Pub Date : 2025-05-09 DOI:10.1002/eji.202451642

Jens Niemann, Maren Claus, Vanna Imširović, Carsten Watzl

引用次数: 0

Abstract

Upon repeated target cell contact serial degranulating NK cells are identified by multiple staining events using differentially labeled anti-CD107a (LAMP1) antibodies. This flow-cytometry-based method allows for the characterization and isolation of serial degranulating NK cells.

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重复CD107a染色可以鉴定一系列脱颗粒NK细胞

在重复的靶细胞接触后，使用差异标记的抗cd107a （LAMP1）抗体通过多次染色事件鉴定出一系列脱颗粒NK细胞。这种基于流式细胞术的方法允许对序列脱颗粒NK细胞进行表征和分离。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

European Journal of Immunology 医学-免疫学

CiteScore

8.30

自引率

3.70%

发文量

224

审稿时长

2 months

期刊介绍： The European Journal of Immunology (EJI) is an official journal of EFIS. Established in 1971, EJI continues to serve the needs of the global immunology community covering basic, translational and clinical research, ranging from adaptive and innate immunity through to vaccines and immunotherapy, cancer, autoimmunity, allergy and more. Mechanistic insights and thought-provoking immunological findings are of interest, as are studies using the latest omics technologies. We offer fast track review for competitive situations, including recently scooped papers, format free submission, transparent and fair peer review and more as detailed in our policies.