Opioids in pain medicine

IF 0.2 Q4 ANESTHESIOLOGY

Anaesthesia and Intensive Care Medicine Pub Date : 2025-05-01 DOI:10.1016/j.mpaic.2025.03.002

Adam Green, Helen Laycock

引用次数: 0

Abstract

Opioids represent an important class of analgesic medication and are effective in moderate to severe acute and cancer pain management. Opioids bind to G protein coupled receptors leading to a variety of physiological effects, including analgesia. Choosing the most appropriate opioid for each individual patient will depend upon the opioids individual pharmacokinetics and pharmacodynamics, their actions across different physiological systems, side effect profiles, available routes of administration and patient factors that impact on drug efficacy. Appropriate governance and opioid stewardship is required to ensure safety and avoidance of misuse.

查看原文本刊更多论文

止痛药中的阿片类药物

阿片类药物是一类重要的镇痛药物，在中度至重度急性疼痛和癌症疼痛管理中有效。阿片结合G蛋白偶联受体导致多种生理作用，包括镇痛。为每位患者选择最合适的阿片类药物将取决于阿片类药物的个体药代动力学和药效学，它们在不同生理系统中的作用，副作用概况，可用的给药途径以及影响药物疗效的患者因素。需要适当的治理和阿片类药物管理，以确保安全和避免滥用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Anaesthesia and Intensive Care Medicine ANESTHESIOLOGY-

CiteScore

0.50

自引率

0.00%

发文量

152

期刊介绍： Anaesthesia and Intensive Care Medicine, an invaluable source of up-to-date information, with the curriculum of both the Primary and Final FRCA examinations covered over a three-year cycle. Published monthly this ever-updating text book will be an invaluable source for both trainee and experienced anaesthetists. The enthusiastic editorial board, under the guidance of two eminent and experienced series editors, ensures Anaesthesia and Intensive Care Medicine covers all the key topics in a comprehensive and authoritative manner. Articles now include learning objectives and eash issue features MCQs, facilitating self-directed learning and enabling readers at all levels to test their knowledge. Each issue is divided between basic scientific and clinical sections. The basic science articles include anatomy, physiology, pharmacology, physics and clinical measurement, while the clinical sections cover anaesthetic agents and techniques, assessment and perioperative management. Further sections cover audit, trials, statistics, ethical and legal medicine, and the management of acute and chronic pain.